5VLJ
Cryo-EM structure of yeast cytoplasmic dynein with Walker B mutation at AAA3 in presence of ATP-VO4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dynein heavy chain, cytoplasmic | polymer | 2376 | 272666.3 | 1 | UniProt (P36022) Pfam (PF08393) Pfam (PF18198) Pfam (PF12774) Pfam (PF21499) Pfam (PF12775) Pfam (PF22597) Pfam (PF12780) Pfam (PF12777) Pfam (PF12781) Pfam (PF03028) | Saccharomyces cerevisiae (Baker's yeast) | Dynein heavy chain, cytosolic, DYHC, Cytoplasmic dynein-1 |
| 2 | B, C (B, C) | Nuclear distribution protein PAC1 | polymer | 354 | 40645.4 | 2 | UniProt (A6ZPA6) Pfam (PF00400) | Saccharomyces cerevisiae (Baker's yeast) | Lissencephaly-1 homolog, LIS-1, nudF homolog, Lis1 |
Sequence modifications
A: 1448 - 3028 (UniProt: P36022)
A: 3298 - 4092 (UniProt: P36022)
| PDB | External Database | Details |
|---|---|---|
| Phe 1575 | Leu 1575 | conflict |
| Ser 1578 | Phe 1578 | conflict |
| Glu 1668 | Gln 1668 | conflict |
| Val 1777 | Ile 1777 | conflict |
| Val 1984 | Ile 1984 | conflict |
| Val 2936 | Ile 2936 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly 3343 | Ala 3343 | conflict |
| Val 3444 | Ile 3444 | conflict |
| Arg 3556 | Lys 3556 | conflict |
| Asp 3742 | Asn 3742 | conflict |
| Val 3895 | Phe 3895 | conflict |
| Asp 4072 | Asn 4072 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 353957.1 | |
| All* | Total formula weight | 353957.1 |
