5VLJ
Cryo-EM structure of yeast cytoplasmic dynein with Walker B mutation at AAA3 in presence of ATP-VO4
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Dynein heavy chain, cytoplasmic | polymer | 2376 | 272666.3 | 1 | UniProt (P36022) Pfam (PF08393) Pfam (PF18198) Pfam (PF12774) Pfam (PF21499) Pfam (PF12775) Pfam (PF22597) Pfam (PF12780) Pfam (PF12777) Pfam (PF12781) Pfam (PF03028) In PDB | Saccharomyces cerevisiae (Baker's yeast) | Dynein heavy chain, cytosolic, DYHC, Cytoplasmic dynein-1 |
2 | B, C | Nuclear distribution protein PAC1 | polymer | 354 | 40645.4 | 2 | UniProt (A6ZPA6) Pfam (PF00400) In PDB | Saccharomyces cerevisiae (Baker's yeast) | Lissencephaly-1 homolog, LIS-1, nudF homolog, Lis1 |
Sequence modifications
A: 1448 - 3028 (UniProt: P36022)
A: 3298 - 4092 (UniProt: P36022)
PDB | External Database | Details |
---|---|---|
Phe 1575 | Leu 1575 | conflict |
Ser 1578 | Phe 1578 | conflict |
Glu 1668 | Gln 1668 | conflict |
Val 1777 | Ile 1777 | conflict |
Val 1984 | Ile 1984 | conflict |
Val 2936 | Ile 2936 | conflict |
PDB | External Database | Details |
---|---|---|
Gly 3343 | Ala 3343 | conflict |
Val 3444 | Ile 3444 | conflict |
Arg 3556 | Lys 3556 | conflict |
Asp 3742 | Asn 3742 | conflict |
Val 3895 | Phe 3895 | conflict |
Asp 4072 | Asn 4072 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 353957.1 | |
All* | Total formula weight | 353957.1 |