5VHE

DHX36 in complex with the c-Myc G-quadruplex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	DEAH (Asp-Glu-Ala-His) box polypeptide 36	polymer	933	107181.8	1	UniProt (Q05B79) Pfam (PF00270) Pfam (PF00271) Pfam (PF04408) Pfam (PF21010) Pfam (PF07717) Pfam (PF26026)	Bos taurus (Bovine)
2	B (B)	DNA (5'-D(*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*TP*TP*TP*TP*TP*T)-3')	polymer	24	7573.9	1		Homo sapiens
3	C, D (B)	POTASSIUM ION	non-polymer		39.1	2	Chemie (K)

Sequence modifications

A: 56 - 1010 (UniProt: Q05B79)

PDB	External Database	Details
Gly 55	-	expression tag
-	Pro 132	deletion
-	Ala 133	deletion
-	Glu 134	deletion
-	Asn 135	deletion
-	Lys 136	deletion
-	Pro 137	deletion
-	Asn 138	deletion
-	Ser 139	deletion
-	Val 140	deletion
-	Lys 141	deletion
-	Asn 142	deletion
-	Val 143	deletion
-	Glu 144	deletion
-	His 145	deletion
-	Gln 146	deletion
-	Glu 147	deletion
-	Lys 148	deletion
-	Lys 149	deletion
-	Met 150	deletion
-	Ile 151	deletion
-	Asn 152	deletion
-	Gln 153	deletion
-	Glu 154	deletion
-	Lys 155	deletion
-	Arg 156	deletion
-	Pro 157	deletion
-	Phe 158	deletion
-	Arg 159	deletion
-	Ile 160	deletion
-	Arg 161	deletion
-	Asp 162	deletion
-	Lys 163	deletion
Tyr 435	Glu 435	conflict
Tyr 436	Glu 436	conflict
Tyr 437	Lys 437	conflict
Ala 752	Lys 752	conflict
Ala 753	Asp 753	conflict
Ala 755	Lys 755	conflict
Pro 1011	-	expression tag
His 1012	-	expression tag
His 1013	-	expression tag
His 1014	-	expression tag
His 1015	-	expression tag
His 1016	-	expression tag
His 1017	-	expression tag
His 1018	-	expression tag
His 1019	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	114755.6
Non-Polymers*	Number of molecules	2
	Total formula weight	78.2
All*	Total formula weight	114833.8

*Water molecules are not included.