5VGB
Crystal structure of NmeCas9 HNH domain bound to anti-CRISPR AcrIIC1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CRISPR-associated endonuclease Cas9 | polymer | 142 | 16805.8 | 1 | UniProt (X5EPV9) Pfam (PF13395) | Neisseria meningitidis | |
| 2 | B (B) | Anti-CRISPR protein (AcrIIC1) | polymer | 86 | 9637.9 | 1 | UniProt (by SIFTS) (A0A2D0TCG3) | Neisseria meningitidis | |
| 3 | C, D, F (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | E (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | G, H (A, B) | water | water | 18.0 | 145 | Chemie (HOH) |
Sequence modifications
A: 5 - 142 (UniProt: X5EPV9)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Ala 2 | - | expression tag |
| Ala 3 | - | expression tag |
| Ser 4 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 26443.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 372.3 | |
| All* | Total formula weight | 26816.0 |
