5VEU

Human Cytochrome P450 3A5 (CYP3A5)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Cytochrome P450 3A5	polymer	480	54862.6	12	UniProt (P20815) Pfam (PF00067) In PDB	Homo sapiens (Human)	CYPIIIA5,Cytochrome P450 HLp2,Cytochrome P450-PCN3
2	L, A, B, C, D...	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	12	Chemie (HEM)
3	A, B, H	RITONAVIR	non-polymer		720.9	3	BIRD (PRD_001001) Chemie (RIT)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: 24 - 497 (UniProt: P20815)

PDB	External Database	Details
Met 22	-	initiating methionine
Ala 23	-	expression tag
His 498	-	expression tag
His 499	-	expression tag
His 500	-	expression tag
His 501	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	658351.0
Non-Polymers*	Number of molecules	15
	Total formula weight	9560.7
All*	Total formula weight	667911.7

*Water molecules are not included.