5VAM
BRAF in Complex with RAF709
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Serine/threonine-protein kinase B-raf | polymer | 281 | 31913.9 | 2 | UniProt (P15056) Pfam (PF07714) In PDB | Homo sapiens (Human) | Proto-oncogene B-Raf,p94,v-Raf murine sarcoma viral oncogene homolog B1 |
| 2 | A, B | N-{2-methyl-5'-(morpholin-4-yl)-6'-[(oxan-4-yl)oxy][3,3'-bipyridin]-5-yl}-3-(trifluoromethyl)benzamide | non-polymer | 542.5 | 2 | Chemie (92J) | |||
| 3 | water | water | 18.0 | 271 | Chemie (HOH) |
Sequence modifications
A, B: 445 - 723 (UniProt: P15056)
| PDB | External Database | Details |
|---|---|---|
| Gly 443 | - | expression tag |
| Ser 444 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63827.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1085.1 | |
| All* | Total formula weight | 64912.9 |
