5V4M
Structure of HLA-DR15 with bound alpha3(135-145) peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (D, A, G, J) | HLA-DRA1 | polymer | 189 | 21919.6 | 4 | UniProt (P01903) Pfam (PF00993) Pfam (PF07654) | Homo sapiens (Human) | MHC class II antigen DRA |
| 2 | B, D, F, H (F, C, I, L) | alpha3(135-145)-HLA-DRB1*15:01 | polymer | 216 | 24644.4 | 4 | UniProt (P01911) Pfam (PF00969) Pfam (PF07654) | Homo sapiens (Human) | DW2.2/DR2.2,MHC class II antigen DRB1*15,DW2.2/DR2.2,MHC class II antigen DRB1*15, chimeric construct,DW2.2/DR2.2,MHC class II antigen DRB1*15, chimeric construct |
| 3 | I, K (B, H) | alpha-L-fucopyranose-(1-3)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 513.5 | 2 | In PDB GlyTouCan (G04836KE) | |||
| 4 | J, L (E, K) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 5 | M, N, O, P (D, A, J) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 6 | Q, R, S, T, U... (D, F, A, C, G...) | water | water | 18.0 | 655 | Chemie (HOH) |
Sequence modifications
D, A, G, J: 1 - 181 (UniProt: P01903)
F, C, I, L: -2 - 8 (PDB: 5V4M)
F, C, I, L: 247 - 437 (UniProt: P01911)
| PDB | External Database | Details |
|---|---|---|
| Thr 182 | - | expression tag |
| Ser 183 | - | expression tag |
| Gly 184 | - | expression tag |
| Asp 185 | - | expression tag |
| Asp 186 | - | expression tag |
| Asp 187 | - | expression tag |
| Asp 188 | - | expression tag |
| Lys 189 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 233 | - | linker |
| Ser 234 | - | linker |
| Gly 235 | - | linker |
| Gly 236 | - | linker |
| Ser 237 | - | linker |
| Ile 238 | - | linker |
| Glu 239 | - | linker |
| Gly 240 | - | linker |
| Arg 241 | - | linker |
| Gly 242 | - | linker |
| Gly 243 | - | linker |
| Ser 244 | - | linker |
| Gly 245 | - | linker |
| Ala 246 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 186256.1 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1875.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 189016.7 |
