5V4M
Structure of HLA-DR15 with bound alpha3(135-145) peptide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006955 | biological_process | immune response |
| A | 0016020 | cellular_component | membrane |
| A | 0019882 | biological_process | antigen processing and presentation |
| A | 0042613 | cellular_component | MHC class II protein complex |
| C | 0006955 | biological_process | immune response |
| C | 0016020 | cellular_component | membrane |
| C | 0019882 | biological_process | antigen processing and presentation |
| C | 0042613 | cellular_component | MHC class II protein complex |
| D | 0006955 | biological_process | immune response |
| D | 0016020 | cellular_component | membrane |
| D | 0019882 | biological_process | antigen processing and presentation |
| D | 0042613 | cellular_component | MHC class II protein complex |
| F | 0006955 | biological_process | immune response |
| F | 0016020 | cellular_component | membrane |
| F | 0019882 | biological_process | antigen processing and presentation |
| F | 0042613 | cellular_component | MHC class II protein complex |
| G | 0006955 | biological_process | immune response |
| G | 0016020 | cellular_component | membrane |
| G | 0019882 | biological_process | antigen processing and presentation |
| G | 0042613 | cellular_component | MHC class II protein complex |
| I | 0006955 | biological_process | immune response |
| I | 0016020 | cellular_component | membrane |
| I | 0019882 | biological_process | antigen processing and presentation |
| I | 0042613 | cellular_component | MHC class II protein complex |
| J | 0006955 | biological_process | immune response |
| J | 0016020 | cellular_component | membrane |
| J | 0019882 | biological_process | antigen processing and presentation |
| J | 0042613 | cellular_component | MHC class II protein complex |
| L | 0006955 | biological_process | immune response |
| L | 0016020 | cellular_component | membrane |
| L | 0019882 | biological_process | antigen processing and presentation |
| L | 0042613 | cellular_component | MHC class II protein complex |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YDCRVEH |
| Chain | Residue | Details |
| D | TYR161-HIS167 | |
| F | TYR418-HIS424 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819 |
| Chain | Residue | Details |
| C | ASP304 | |
| C | TRP308 | |
| C | HIS328 | |
| C | ASN329 | |
| I | ASP304 | |
| I | TRP308 | |
| I | HIS328 | |
| I | ASN329 | |
| L | ASP304 | |
| L | TRP308 | |
| L | HIS328 | |
| L | ASN329 | |
| F | ASP304 | |
| F | TRP308 | |
| F | HIS328 | |
| F | ASN329 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:8145819 |
| Chain | Residue | Details |
| C | ARG340 | |
| I | ARG340 | |
| L | ARG340 | |
| F | ARG340 | |
| G | GLY49 | |
| G | ALA52 | |
| J | GLY49 | |
| J | ALA52 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19303388, ECO:0000269|PubMed:24190431 |
| Chain | Residue | Details |
| F | ASN266 | |
| C | ASN266 | |
| I | ASN266 | |
| L | ASN266 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | SITE: Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819 |
| Chain | Residue | Details |
| D | SER53 | |
| A | SER53 | |
| G | SER53 | |
| J | SER53 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | SITE: Pathogen-derived peptide antigen => ECO:0000269|PubMed:23260142, ECO:0007744|PDB:4GBX |
| Chain | Residue | Details |
| D | GLU55 | |
| A | GLU55 | |
| G | GLU55 | |
| J | GLU55 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | SITE: Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4GBX |
| Chain | Residue | Details |
| D | ASN62 | |
| A | ASN62 | |
| G | ASN62 | |
| J | ASN62 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | SITE: Pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4FQX, ECO:0007744|PDB:4GBX |
| Chain | Residue | Details |
| D | ASN69 | |
| A | ASN69 | |
| G | ASN69 | |
| J | ASN69 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | SITE: Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4FQX, ECO:0007744|PDB:4GBX |
| Chain | Residue | Details |
| D | ARG76 | |
| A | ARG76 | |
| G | ARG76 | |
| J | ARG76 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 8 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:7477400 |
| Chain | Residue | Details |
| D | ASN78 | |
| D | ASN118 | |
| A | ASN78 | |
| A | ASN118 | |
| G | ASN78 | |
| G | ASN118 | |
| J | ASN78 | |
| J | ASN118 |
