5UXH
Structure of Human POFUT1 in complex with GDP-fucose
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | GDP-fucose protein O-fucosyltransferase 1 | polymer | 367 | 41872.0 | 2 | UniProt (Q9H488) Pfam (PF10250) | Homo sapiens (Human) | Peptide-O-fucosyltransferase 1,O-FucT-1 |
| 2 | C, E (A, B) | GUANOSINE-5'-DIPHOSPHATE-BETA-L-FUCOPYRANOSE | non-polymer | 589.3 | 2 | Chemie (GFB) | |||
| 3 | D, F (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 72 | Chemie (HOH) |
Sequence modifications
A, B: 24 - 384 (UniProt: Q9H488)
| PDB | External Database | Details |
|---|---|---|
| Ala 160 | Asn 160 | engineered mutation |
| His 385 | - | expression tag |
| His 386 | - | expression tag |
| His 387 | - | expression tag |
| His 388 | - | expression tag |
| His 389 | - | expression tag |
| His 390 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 83744.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1621.1 | |
| All* | Total formula weight | 85365.2 |
