5UXF

Crystal Structure of mouse RECON (AKR1C13) in complex with Cyclic di-AMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Dihydrodiol dehydrogenase	polymer	342	39291.0	1	UniProt (Q54A37) Pfam (PF00248) UniProt (by SIFTS) (Q8VC28) In PDB	Mus musculus (Mouse)
2	A	(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide	non-polymer		658.4	1	Chemie (2BA)
3		water	water		18.0	432	Chemie (HOH)

Sequence modifications

A: 1 - 323 (UniProt: Q54A37)

PDB	External Database	Details
Met -18	-	initiating methionine
Gly -17	-	expression tag
Ser -16	-	expression tag
Asp -15	-	expression tag
Lys -14	-	expression tag
Ile -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag
Ala 68	Lys 68	engineered mutation
Ala 70	Lys 70	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	39291.0
Non-Polymers*	Number of molecules	1
	Total formula weight	658.4
All*	Total formula weight	39949.4

*Water molecules are not included.