Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004033 | molecular_function | aldo-keto reductase (NADPH) activity |
| A | 0006805 | biological_process | xenobiotic metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | binding site for residue 2BA A 401 |
| Chain | Residue |
| A | TYR24 |
| A | GLN270 |
| A | SER271 |
| A | GLU276 |
| A | GLU279 |
| A | ASN280 |
| A | HOH506 |
| A | HOH536 |
| A | HOH538 |
| A | HOH539 |
| A | HOH547 |
| A | TYR55 |
| A | HOH552 |
| A | HOH554 |
| A | HOH608 |
| A | HOH643 |
| A | HOH660 |
| A | HOH771 |
| A | TYR216 |
| A | GLY217 |
| A | ALA218 |
| A | LEU219 |
| A | GLY220 |
| A | THR221 |
| A | ALA253 |
Functional Information from PROSITE/UniProt
| site_id | PS00062 |
| Number of Residues | 18 |
| Details | ALDOKETO_REDUCTASE_2 Aldo/keto reductase family signature 2. LeeckdaglVKSIGVSNF |
| Chain | Residue | Details |
| A | LEU151-PHE168 | |
| site_id | PS00798 |
| Number of Residues | 18 |
| Details | ALDOKETO_REDUCTASE_1 Aldo/keto reductase family signature 1. GYRHVDTAyayqvEeeIG |
| Chain | Residue | Details |
| A | GLY45-GLY62 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor => ECO:0000250 |
| Chain | Residue | Details |
| A | TYR55 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | BINDING: BINDING => ECO:0000269|Ref.6 |
| Chain | Residue | Details |
| A | GLY20 | |
| A | ASP50 | |
| A | TYR55 | |
| A | SER166 | |
| A | GLN190 | |
| A | TYR216 | |
| A | GLN270 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS117 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | SITE: Lowers pKa of active site Tyr => ECO:0000250 |
| Chain | Residue | Details |
| A | LYS84 | |
