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5UXC

Crystal structure of macrolide 2'-phosphotransferase MphH from Brachybacterium faecium in complex with GDP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Predicted aminoglycoside phosphotransferasepolymer29932289.51UniProt (C7MEP1)
Pfam (PF01636)
Brachybacterium faecium
2B
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
3C
(A)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
4D, E, F
(A)
SULFATE IONnon-polymer96.13Chemie (SO4)
5G, H
(A)
AZITHROMYCINnon-polymer749.02Chemie (ZIT)
6I
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
7J, K
(A)
CHLORIDE IONnon-polymer35.52Chemie (CL)
8L
(A)
TRIETHYLENE GLYCOLnon-polymer150.21Chemie (PGE)
9M
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
10N
(A)
waterwater18.0465Chemie (HOH)
Sequence modifications
A: 1 - 298 (UniProt: C7MEP1)
PDBExternal DatabaseDetails
Gly 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight32289.5
Non-Polymers*Number of molecules12
Total formula weight2661.8
All*Total formula weight34951.3
*Water molecules are not included.

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PDB entries from 2025-06-18

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