5UWX
Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P176
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase | polymer | 363 | 38441.3 | 4 | UniProt (A0A127ELD1) | Clostridium perfringens | IMPDH,IMPDH |
| 2 | E, I, M, Q (A, B, C, D) | N-{2-chloro-5-[({2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}carbamoyl)amino]phenyl}-alpha-D-ribofuranosylamine | non-polymer | 476.0 | 4 | Chemie (8L7) | |||
| 3 | F, J, N, R (A, B, C, D) | INOSINIC ACID | non-polymer | 348.2 | 4 | Chemie (IMP) PubChem (177678963) PubChem (135464200) PubChem (135533971) PubChem (138454308) PubChem (135398640) PubChem (135402036) PubChem (135449337) PubChem (135486133) PubChem (135530792) PubChem (135567013) PubChem (135705234) PubChem (135854804) PubChem (135889742) PubChem (136026456) PubChem (136073920) PubChem (136217866) PubChem (136259539) PubChem (136716177) PubChem (136766861) PubChem (136811071) PubChem (137162990) PubChem (137168789) PubChem (137257909) PubChem (162510533) PubChem (174152734) | |||
| 4 | G, K, P, S (A, B, C, D) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 4 | Chemie (MPD) | |||
| 5 | H, O, T (A, C, D) | ACETIC ACID | non-polymer | 60.1 | 3 | Chemie (ACY) | |||
| 6 | L (B) | (4R)-2-METHYLPENTANE-2,4-DIOL | non-polymer | 118.2 | 1 | Chemie (MRD) PubChem (7870) PubChem (5288834) PubChem (5288845) | |||
| 7 | U, V, W, X (A, B, C, D) | water | water | 18.0 | 477 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 88 (UniProt: A0A127ELD1)
A, B, C, D: 216 - 484 (UniProt: A0A127ELD1)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 89 | - | linker |
| Gly 90 | - | linker |
| Gly 91 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 153765.1 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 4067.7 | |
| All* | Total formula weight | 157832.8 |
