5UUM
Human Mcl-1 in complex with a Bfl-1-specific selected peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Induced myeloid leukemia cell differentiation protein Mcl-1 | polymer | 156 | 17823.3 | 2 | UniProt (Q07820) Pfam (PF00452) | Homo sapiens (Human) | Bcl-2-like protein 3,Bcl2-L-3,Bcl-2-related protein EAT/mcl1,mcl1/EAT |
| 2 | C, D (C, D) | Bfl-1 specific peptide FS2 | polymer | 25 | 2652.0 | 2 | synthetic construct | ||
| 3 | E, F, G, H, J... (A, B) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 4 | I, N (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | O, P, Q, R (A, B, C, D) | water | water | 18.0 | 192 | Chemie (HOH) |
Sequence modifications
A, B: 172 - 325 (UniProt: Q07820)
| PDB | External Database | Details |
|---|---|---|
| Gly 170 | - | expression tag |
| Ser 171 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 40950.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 715.4 | |
| All* | Total formula weight | 41665.8 |
