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5UUM

Human Mcl-1 in complex with a Bfl-1-specific selected peptide

Functional Information from GO Data
ChainGOidnamespacecontents
A0042981biological_processregulation of apoptotic process
B0042981biological_processregulation of apoptotic process
Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue ZN A 401
ChainResidue
AHIS252
BASP304
BASP323
BGLU325

site_idAC2
Number of Residues4
Detailsbinding site for residue ZN A 402
ChainResidue
AGLU317
AHIS320
AGLU322
DASP15

site_idAC3
Number of Residues4
Detailsbinding site for residue ZN A 403
ChainResidue
AASP242
AHIS277
AHOH553
AASP236

site_idAC4
Number of Residues4
Detailsbinding site for residue ZN A 404
ChainResidue
AHIS224
AHOH551
CASP16
CGLN20

site_idAC5
Number of Residues6
Detailsbinding site for residue SO4 A 405
ChainResidue
AARG248
AHIS252
AHOH507
AHOH536
BARG300
CHOH108

site_idAC6
Number of Residues4
Detailsbinding site for residue ZN B 401
ChainResidue
BGLU317
BHIS320
BGLU322
CASP15

site_idAC7
Number of Residues4
Detailsbinding site for residue ZN B 402
ChainResidue
AASP304
AASP323
AGLU325
BHIS252

site_idAC8
Number of Residues3
Detailsbinding site for residue ZN B 403
ChainResidue
BASP236
BASP242
BHIS277

site_idAC9
Number of Residues4
Detailsbinding site for residue ZN B 404
ChainResidue
BHIS224
BHOH531
DASP16
DGLN20

site_idAD1
Number of Residues5
Detailsbinding site for residue SO4 B 405
ChainResidue
AARG303
AHOH505
BHIS252
BHOH541
DHOH103

Functional Information from PROSITE/UniProt
site_idPS01080
Number of Residues20
DetailsBH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. VFsDGvtNWGRIVTLIsFGA
ChainResidueDetails
AVAL253-ALA272

site_idPS01258
Number of Residues12
DetailsBH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WLvkqRGWDgFV
ChainResidueDetails
ATRP305-VAL316

site_idPS01259
Number of Residues15
DetailsBH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. AletLRrVGDGVQRN
ChainResidueDetails
AALA209-ASN223

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)
ChainResidueDetails
ALYS194
ALYS197
BLYS194
BLYS197

226707

PDB entries from 2024-10-30

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