5US1
Crystal structure of aminoglycoside acetyltransferase AAC(2')-Ia in complex with N2'-acetylgentamicin C1A and coenzyme A
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Aminoglycoside 2'-N-acetyltransferase | polymer | 189 | 21189.9 | 12 | UniProt (Q52424) Pfam (PF13527) In PDB | Providencia stuartii | AAC(2')-Ia |
2 | I, K, L, A, B... | (1R,2S,3S,4R,6S)-4,6-diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-2-hydroxycyclohexyl 2-(acetylamino)-6-amino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranoside | non-polymer | 491.6 | 10 | Chemie (8MM) | |||
3 | J, A, D, F, H | D(-)-TARTARIC ACID | non-polymer | 150.1 | 5 | Chemie (TAR) | |||
4 | C | ACETYL COENZYME *A | non-polymer | 809.6 | 1 | Chemie (ACO) | |||
5 | I, K, C | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
6 | I, L, E | COENZYME A | non-polymer | 767.5 | 3 | Chemie (COA) | |||
7 | water | water | 18.0 | 579 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 1 - 178 (UniProt: Q52424)
PDB | External Database | Details |
---|---|---|
Gly -10 | - | expression tag |
Leu -9 | - | expression tag |
Val -8 | - | expression tag |
Pro -7 | - | expression tag |
Arg -6 | - | expression tag |
Gly -5 | - | expression tag |
Ser -4 | - | expression tag |
His -3 | - | expression tag |
Met -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 254279.4 | |
Non-Polymers* | Number of molecules | 22 |
Total formula weight | 9054.7 | |
All* | Total formula weight | 263334.1 |