5UOS
Crystal Structure of CblC (MMACHC) (1-238), a human B12 processing enzyme, complexed with an Antivitamin B12
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Methylmalonic aciduria and homocystinuria type C protein | polymer | 241 | 27489.5 | 1 | UniProt (Q9Y4U1) Pfam (PF16690) In PDB | Homo sapiens (Human) | CblC,Cyanocobalamin reductase (cyanide-eliminating) |
2 | A | COBALAMIN | non-polymer | 1330.4 | 1 | Chemie (B12) | |||
3 | A | 1-ethynyl-2,4-difluorobenzene | non-polymer | 138.1 | 1 | Chemie (8FS) | |||
4 | A | GLUTATHIONE | non-polymer | 307.3 | 1 | Chemie (GSH) | |||
5 | A | 2-PHENYLAMINO-ETHANESULFONIC ACID | non-polymer | 201.2 | 1 | Chemie (171) | |||
6 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
7 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
8 | water | water | 18.0 | 75 | Chemie (HOH) |
Sequence modifications
A: 1 - 238 (UniProt: Q9Y4U1)
PDB | External Database | Details |
---|---|---|
Ser -2 | - | expression tag |
Asn -1 | - | expression tag |
Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 27489.5 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 2192.2 | |
All* | Total formula weight | 29681.7 |