5UN5
Frizzled-8 complex with designed surrogate Wnt agonist, crystal form 1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, A | Frizzled-8 | polymer | 129 | 14961.1 | 2 | UniProt (Q9H461) Pfam (PF01392) In PDB | Homo sapiens (Human) | hFz8 |
2 | D, C | Designed Wnt agonist B12 | polymer | 123 | 13825.0 | 2 | synthetic construct | ||
3 | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 123 (UniProt: Q9H461)
PDB | External Database | Details |
---|---|---|
Gln 22 | Asn 49 | conflict |
His 124 | - | expression tag |
His 125 | - | expression tag |
His 126 | - | expression tag |
His 127 | - | expression tag |
His 128 | - | expression tag |
His 129 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 57572.2 | |
All* | Total formula weight | 57572.2 |