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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

5UMD

Structure of the Plasmodium falciparum 80S ribosome bound to the antimalarial drug mefloquine

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A28S ribosomal RNApolymer37881216212.11GenBank (1013064538)Plasmodium falciparum 3D7
2B5S ribosomal RNApolymer11938410.91GenBank (1016052399)Plasmodium falciparum 3D7
3C5.8S ribosomal RNApolymer15951206.51GenBank (1013064403)Plasmodium falciparum 3D7
4D60S ribosomal protein L2polymer26028065.01UniProt (Q8I3T9)
Pfam (PF00181)
Pfam (PF03947)
In PDB		Plasmodium falciparum 3D7
5E60S ribosomal protein L3polymer38644318.21UniProt (Q8IJC6)
Pfam (PF00297)
In PDB		Plasmodium falciparum 3D760S ribosomal protein L3,putative
6F60S ribosomal protein L4polymer41146311.71UniProt (Q8I431)
Pfam (PF00573)
Pfam (PF14374)
In PDB		Plasmodium falciparum 3D7
7G60S ribosomal protein L11a, putativepolymer17320268.71UniProt (Q8IBQ6)
Pfam (PF00281)
Pfam (PF00673)
In PDB		Plasmodium falciparum 3D7
8H60S ribosomal protein L6, putativepolymer19021638.61UniProt (Q8IE85)
Pfam (PF00347)
In PDB		Plasmodium falciparum 3D7
9I60S ribosomal protein L6-2, putativepolymer22125587.61UniProt (Q8IDV1)
In PDB		Plasmodium falciparum 3D7
10J60S ribosomal protein L7-3, putativepolymer28332760.51UniProt (Q8ILL2)
Pfam (PF01248)
In PDB		Plasmodium falciparum 3D7
11K60S ribosomal protein L13, putativepolymer20223805.31UniProt (Q8IJZ7)
Pfam (PF00572)
In PDB		Plasmodium falciparum 3D7
12L60S ribosomal protein L13polymer21525454.11UniProt (Q8IAX6)
Pfam (PF01294)
In PDB		Plasmodium falciparum 3D7
13M60S ribosomal protein L23, putativepolymer13915015.71UniProt (Q8IE09)
Pfam (PF00238)
In PDB		Plasmodium falciparum 3D7
14N60S ribosomal protein L14, putativepolymer16519340.41UniProt (Q8ILE8)
Pfam (PF01929)
In PDB		Plasmodium falciparum 3D7
15O60S ribosomal protein L27a, putativepolymer14816765.81UniProt (C6KT23)
Pfam (PF00828)
In PDB		Plasmodium falciparum 3D7
16PRibosomal protein L15polymer20524197.71UniProt (C0H4A6)
Pfam (PF00827)
In PDB		Plasmodium falciparum 3D7
17Q60S ribosomal protein L10, putativepolymer21925265.51UniProt (Q8ILV2)
Pfam (PF00252)
In PDB		Plasmodium falciparum 3D7
18R60S ribosomal protein L5, putativepolymer29434067.41UniProt (Q8ILL3)
Pfam (PF17144)
Pfam (PF14204)
In PDB		Plasmodium falciparum 3D7
19S60S ribosomal protein L18-2, putativepolymer18721508.81UniProt (C0H5G3)
Pfam (PF17135)
In PDB		Plasmodium falciparum 3D7
20T60S ribosomal protein L19polymer18221641.11UniProt (C6KSY6)
Pfam (PF01280)
In PDB		Plasmodium falciparum 3D7
21U60S ribosomal protein L18apolymer18421793.61UniProt (Q8IDS6)
Pfam (PF01775)
In PDB		Plasmodium falciparum 3D7
22V60S ribosomal protein L21polymer16118840.21UniProt (Q8ILK3)
Pfam (PF01157)
In PDB		Plasmodium falciparum 3D760S ribosomal protein L21e,putative
23W60S ribosomal protein L17, putativepolymer20323469.91UniProt (Q8IDI5)
Pfam (PF00237)
In PDB		Plasmodium falciparum 3D7
24X60S ribosomal protein L22, putativepolymer13916422.91UniProt (Q8IB51)
Pfam (PF01776)
In PDB		Plasmodium falciparum 3D7
25Y60S ribosomal protein L23polymer19022152.71UniProt (Q8IE82)
Pfam (PF03939)
Pfam (PF00276)
In PDB		Plasmodium falciparum 3D7
26Z60S ribosomal protein L26, putativepolymer12614855.71UniProt (O77364)
Pfam (PF16906)
Pfam (PF00467)
In PDB		Plasmodium falciparum 3D7
27060S ribosomal protein L24, putativepolymer16219295.91UniProt (Q8IEM3)
Pfam (PF01246)
In PDB		Plasmodium falciparum 3D7
28160S ribosomal protein L27polymer14616785.21UniProt (Q8IKM5)
Pfam (PF01777)
In PDB		Plasmodium falciparum 3D760S ribosomal protein L27,putative
29260S ribosomal protein L28polymer12714437.81UniProt (Q8IHU0)
Pfam (PF01778)
In PDB		Plasmodium falciparum 3D760S ribosomal protein L28,putative
30360S ribosomal protein L35, putativepolymer12414787.81UniProt (Q8IIB4)
Pfam (PF00831)
In PDB		Plasmodium falciparum 3D7
31460S ribosomal protein L29, putativepolymer678041.61UniProt (C6S3J6)
Pfam (PF01779)
In PDB		Plasmodium falciparum 3D7Ribosomal protein L29,putative
32560S ribosomal protein L7, putativepolymer25730593.21UniProt (O97250)
Pfam (PF08079)
Pfam (PF00327)
In PDB		Plasmodium falciparum 3D7
33660S ribosomal protein L30e, putativepolymer10811794.81UniProt (Q8IJK8)
Pfam (PF01248)
In PDB		Plasmodium falciparum 3D7
34760S ribosomal protein L31polymer12014099.91UniProt (Q8I463)
Pfam (PF01198)
In PDB		Plasmodium falciparum 3D7
35860S ribosomal protein L32polymer13115565.81UniProt (Q8I3B0)
Pfam (PF01655)
In PDB		Plasmodium falciparum 3D7
36960S ribosomal protein L35Ae, putativepolymer14016306.41UniProt (Q8IHT9)
Pfam (PF01247)
In PDB		Plasmodium falciparum 3D760S ribosomal protein L35ae,putative
37a60S ribosomal protein L34polymer15017407.01UniProt (Q8IBY4)
Pfam (PF01199)
In PDB		Plasmodium falciparum 3D7
38b60S ribosomal protein L36polymer11212825.41UniProt (Q8I713)
Pfam (PF01158)
In PDB		Plasmodium falciparum 3D7
39cRibosomal protein L37polymer9210571.61UniProt (C0H4L5)
Pfam (PF01907)
In PDB		Plasmodium falciparum 3D7
40d60S ribosomal protein L38polymer8710341.71UniProt (Q8II62)
Pfam (PF01781)
In PDB		Plasmodium falciparum 3D760S ribosomal protein L38e,putative
41e60S ribosomal protein L39polymer516540.91UniProt (C0H4H3)
Pfam (PF00832)
In PDB		Plasmodium falciparum 3D7
42fUbiquitin-60S ribosomal protein L40polymer12814645.21UniProt (Q8ID50)
Pfam (PF00240)
Pfam (PF01020)
In PDB		Plasmodium falciparum 3D7
43g60S ribosomal protein L41polymer395108.31UniProt (C6S3G4)
Pfam (PF05162)
In PDB		Plasmodium falciparum 3D760S ribosomal protein L41,putative
44h60S ribosomal protein L37apolymer9610826.11UniProt (O96184)
Pfam (PF01780)
In PDB		Plasmodium falciparum 3D7
45i60S ribosomal protein L44polymer10412194.91UniProt (O97231)
Pfam (PF00935)
In PDB		Plasmodium falciparum 3D7
46K, AMefloquinenon-polymer378.32Chemie (YMZ)
47A, C, M, BMAGNESIUM IONnon-polymer24.3164Chemie (MG)
48a, c, f, h, iZINC IONnon-polymer65.45Chemie (ZN)
Sequence modifications
A: 1 - 3788 (GenBank: 1013064538)
PDBExternal DatabaseDetails
C 821U 1087390conflict
B: 1 - 119 (GenBank: 1016052399)
PDBExternal DatabaseDetails
A 23C 779399conflict
U 24C 779400conflict
G 119U 779495conflict
L: 1 - 215 (UniProt: Q8IAX6)
PDBExternal DatabaseDetails
His 19Arg 19conflict
Arg 20His 20conflict
Cys 201Arg 201conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains45
Total formula weight2131546.0
Non-Polymers*Number of molecules171
Total formula weight5069.7
All*Total formula weight2136615.7
*Water molecules are not included.

222036

PDB entries from 2024-07-03

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