Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5UMD

Structure of the Plasmodium falciparum 80S ribosome bound to the antimalarial drug mefloquine

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0002181	biological_process	cytoplasmic translation
0	0003729	molecular_function	mRNA binding
0	0003735	molecular_function	structural constituent of ribosome
0	0005840	cellular_component	ribosome
0	0006412	biological_process	translation
0	0022625	cellular_component	cytosolic large ribosomal subunit
0	1990904	cellular_component	ribonucleoprotein complex
1	0003735	molecular_function	structural constituent of ribosome
1	0005840	cellular_component	ribosome
1	0006412	biological_process	translation
1	0022625	cellular_component	cytosolic large ribosomal subunit
1	1990904	cellular_component	ribonucleoprotein complex
2	0005840	cellular_component	ribosome
2	0022625	cellular_component	cytosolic large ribosomal subunit
3	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
3	0003729	molecular_function	mRNA binding
3	0003735	molecular_function	structural constituent of ribosome
3	0005840	cellular_component	ribosome
3	0006412	biological_process	translation
3	0015934	cellular_component	large ribosomal subunit
3	0022625	cellular_component	cytosolic large ribosomal subunit
3	1990904	cellular_component	ribonucleoprotein complex
4	0002181	biological_process	cytoplasmic translation
4	0003735	molecular_function	structural constituent of ribosome
4	0005840	cellular_component	ribosome
4	0006412	biological_process	translation
4	0022625	cellular_component	cytosolic large ribosomal subunit
4	1990904	cellular_component	ribonucleoprotein complex
5	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
5	0003723	molecular_function	RNA binding
5	0003735	molecular_function	structural constituent of ribosome
5	0005840	cellular_component	ribosome
5	0006412	biological_process	translation
5	0022625	cellular_component	cytosolic large ribosomal subunit
5	1990904	cellular_component	ribonucleoprotein complex
6	0003723	molecular_function	RNA binding
6	0003735	molecular_function	structural constituent of ribosome
6	0005840	cellular_component	ribosome
6	0006412	biological_process	translation
6	0022625	cellular_component	cytosolic large ribosomal subunit
6	1990904	cellular_component	ribonucleoprotein complex
7	0002181	biological_process	cytoplasmic translation
7	0003735	molecular_function	structural constituent of ribosome
7	0005840	cellular_component	ribosome
7	0006412	biological_process	translation
7	0022625	cellular_component	cytosolic large ribosomal subunit
7	1990904	cellular_component	ribonucleoprotein complex
8	0003735	molecular_function	structural constituent of ribosome
8	0005840	cellular_component	ribosome
8	0006412	biological_process	translation
8	0022625	cellular_component	cytosolic large ribosomal subunit
8	1990904	cellular_component	ribonucleoprotein complex
9	0002181	biological_process	cytoplasmic translation
9	0003735	molecular_function	structural constituent of ribosome
9	0005840	cellular_component	ribosome
9	0006412	biological_process	translation
9	0015934	cellular_component	large ribosomal subunit
9	0022625	cellular_component	cytosolic large ribosomal subunit
9	0042273	biological_process	ribosomal large subunit biogenesis
9	1990904	cellular_component	ribonucleoprotein complex
D	0002181	biological_process	cytoplasmic translation
D	0003723	molecular_function	RNA binding
D	0003735	molecular_function	structural constituent of ribosome
D	0005840	cellular_component	ribosome
D	0006412	biological_process	translation
D	0015934	cellular_component	large ribosomal subunit
D	0022625	cellular_component	cytosolic large ribosomal subunit
D	1990904	cellular_component	ribonucleoprotein complex
E	0003723	molecular_function	RNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
E	0022625	cellular_component	cytosolic large ribosomal subunit
E	1990904	cellular_component	ribonucleoprotein complex
F	0003723	molecular_function	RNA binding
F	0003735	molecular_function	structural constituent of ribosome
F	0005840	cellular_component	ribosome
F	0006412	biological_process	translation
F	0022625	cellular_component	cytosolic large ribosomal subunit
F	1990904	cellular_component	ribonucleoprotein complex
G	0003723	molecular_function	RNA binding
G	0003735	molecular_function	structural constituent of ribosome
G	0005634	cellular_component	nucleus
G	0005737	cellular_component	cytoplasm
G	0005840	cellular_component	ribosome
G	0006412	biological_process	translation
G	0019843	molecular_function	rRNA binding
G	0022625	cellular_component	cytosolic large ribosomal subunit
G	1990904	cellular_component	ribonucleoprotein complex
H	0002181	biological_process	cytoplasmic translation
H	0003723	molecular_function	RNA binding
H	0003735	molecular_function	structural constituent of ribosome
H	0005840	cellular_component	ribosome
H	0006412	biological_process	translation
H	0015934	cellular_component	large ribosomal subunit
H	0019843	molecular_function	rRNA binding
H	0022625	cellular_component	cytosolic large ribosomal subunit
H	1990904	cellular_component	ribonucleoprotein complex
I	0003735	molecular_function	structural constituent of ribosome
I	0005840	cellular_component	ribosome
I	0006412	biological_process	translation
J	0000470	biological_process	maturation of LSU-rRNA
J	0003723	molecular_function	RNA binding
J	0003735	molecular_function	structural constituent of ribosome
J	0005840	cellular_component	ribosome
J	0006412	biological_process	translation
J	0022625	cellular_component	cytosolic large ribosomal subunit
J	1990904	cellular_component	ribonucleoprotein complex
K	0003729	molecular_function	mRNA binding
K	0003735	molecular_function	structural constituent of ribosome
K	0005840	cellular_component	ribosome
K	0006412	biological_process	translation
K	0015934	cellular_component	large ribosomal subunit
K	0017148	biological_process	negative regulation of translation
K	0022625	cellular_component	cytosolic large ribosomal subunit
K	1990904	cellular_component	ribonucleoprotein complex
L	0003723	molecular_function	RNA binding
L	0003735	molecular_function	structural constituent of ribosome
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
L	0022625	cellular_component	cytosolic large ribosomal subunit
L	1990904	cellular_component	ribonucleoprotein complex
M	0003735	molecular_function	structural constituent of ribosome
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0022625	cellular_component	cytosolic large ribosomal subunit
M	0070180	molecular_function	large ribosomal subunit rRNA binding
M	1990904	cellular_component	ribonucleoprotein complex
N	0003723	molecular_function	RNA binding
N	0003735	molecular_function	structural constituent of ribosome
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
N	0020011	cellular_component	apicoplast
N	0022625	cellular_component	cytosolic large ribosomal subunit
N	0022627	cellular_component	cytosolic small ribosomal subunit
N	0042273	biological_process	ribosomal large subunit biogenesis
N	1990904	cellular_component	ribonucleoprotein complex
O	0003735	molecular_function	structural constituent of ribosome
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0015934	cellular_component	large ribosomal subunit
O	0022625	cellular_component	cytosolic large ribosomal subunit
O	1990904	cellular_component	ribonucleoprotein complex
P	0002181	biological_process	cytoplasmic translation
P	0003723	molecular_function	RNA binding
P	0003735	molecular_function	structural constituent of ribosome
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
P	0022625	cellular_component	cytosolic large ribosomal subunit
P	1990904	cellular_component	ribonucleoprotein complex
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0022625	cellular_component	cytosolic large ribosomal subunit
Q	1990904	cellular_component	ribonucleoprotein complex
R	0000027	biological_process	ribosomal large subunit assembly
R	0003723	molecular_function	RNA binding
R	0003735	molecular_function	structural constituent of ribosome
R	0005634	cellular_component	nucleus
R	0005737	cellular_component	cytoplasm
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
R	0008097	molecular_function	5S rRNA binding
R	0022625	cellular_component	cytosolic large ribosomal subunit
R	0022626	cellular_component	cytosolic ribosome
R	1990904	cellular_component	ribonucleoprotein complex
S	0003723	molecular_function	RNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0022625	cellular_component	cytosolic large ribosomal subunit
S	1990904	cellular_component	ribonucleoprotein complex
T	0003723	molecular_function	RNA binding
T	0003735	molecular_function	structural constituent of ribosome
T	0005840	cellular_component	ribosome
T	0006412	biological_process	translation
T	0022625	cellular_component	cytosolic large ribosomal subunit
T	1990904	cellular_component	ribonucleoprotein complex
U	0002181	biological_process	cytoplasmic translation
U	0003735	molecular_function	structural constituent of ribosome
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	0022625	cellular_component	cytosolic large ribosomal subunit
U	1990904	cellular_component	ribonucleoprotein complex
V	0003735	molecular_function	structural constituent of ribosome
V	0005840	cellular_component	ribosome
V	0006412	biological_process	translation
V	0022625	cellular_component	cytosolic large ribosomal subunit
V	1990904	cellular_component	ribonucleoprotein complex
W	0002181	biological_process	cytoplasmic translation
W	0003735	molecular_function	structural constituent of ribosome
W	0005840	cellular_component	ribosome
W	0006412	biological_process	translation
W	0015934	cellular_component	large ribosomal subunit
W	0022625	cellular_component	cytosolic large ribosomal subunit
W	0030684	cellular_component	preribosome
W	1990904	cellular_component	ribonucleoprotein complex
X	0002181	biological_process	cytoplasmic translation
X	0003723	molecular_function	RNA binding
X	0003735	molecular_function	structural constituent of ribosome
X	0005840	cellular_component	ribosome
X	0006412	biological_process	translation
X	0022625	cellular_component	cytosolic large ribosomal subunit
X	1990904	cellular_component	ribonucleoprotein complex
Y	0003723	molecular_function	RNA binding
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005840	cellular_component	ribosome
Y	0006412	biological_process	translation
Y	0019843	molecular_function	rRNA binding
Y	0022625	cellular_component	cytosolic large ribosomal subunit
Y	1990904	cellular_component	ribonucleoprotein complex
Z	0002181	biological_process	cytoplasmic translation
Z	0003723	molecular_function	RNA binding
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005840	cellular_component	ribosome
Z	0006412	biological_process	translation
Z	0015934	cellular_component	large ribosomal subunit
Z	0022625	cellular_component	cytosolic large ribosomal subunit
Z	0042273	biological_process	ribosomal large subunit biogenesis
Z	1990904	cellular_component	ribonucleoprotein complex
a	0003735	molecular_function	structural constituent of ribosome
a	0005840	cellular_component	ribosome
a	0006412	biological_process	translation
a	0022625	cellular_component	cytosolic large ribosomal subunit
a	0042254	biological_process	ribosome biogenesis
a	1990904	cellular_component	ribonucleoprotein complex
b	0002181	biological_process	cytoplasmic translation
b	0003735	molecular_function	structural constituent of ribosome
b	0005840	cellular_component	ribosome
b	0006412	biological_process	translation
b	0022625	cellular_component	cytosolic large ribosomal subunit
b	1990904	cellular_component	ribonucleoprotein complex
c	0003723	molecular_function	RNA binding
c	0003735	molecular_function	structural constituent of ribosome
c	0005840	cellular_component	ribosome
c	0006412	biological_process	translation
c	0008270	molecular_function	zinc ion binding
c	0019843	molecular_function	rRNA binding
c	0022625	cellular_component	cytosolic large ribosomal subunit
c	0046872	molecular_function	metal ion binding
c	1990904	cellular_component	ribonucleoprotein complex
d	0003735	molecular_function	structural constituent of ribosome
d	0005840	cellular_component	ribosome
d	0006412	biological_process	translation
d	0022618	biological_process	protein-RNA complex assembly
d	0022625	cellular_component	cytosolic large ribosomal subunit
d	1990904	cellular_component	ribonucleoprotein complex
e	0003735	molecular_function	structural constituent of ribosome
e	0005840	cellular_component	ribosome
e	0006412	biological_process	translation
e	0022625	cellular_component	cytosolic large ribosomal subunit
e	1990904	cellular_component	ribonucleoprotein complex
f	0003735	molecular_function	structural constituent of ribosome
f	0005634	cellular_component	nucleus
f	0005737	cellular_component	cytoplasm
f	0005840	cellular_component	ribosome
f	0006412	biological_process	translation
f	0006511	biological_process	ubiquitin-dependent protein catabolic process
f	0016567	biological_process	protein ubiquitination
f	0019941	biological_process	modification-dependent protein catabolic process
f	0022625	cellular_component	cytosolic large ribosomal subunit
f	0031386	molecular_function	protein tag activity
f	0031625	molecular_function	ubiquitin protein ligase binding
f	1990904	cellular_component	ribonucleoprotein complex
g	0003735	molecular_function	structural constituent of ribosome
g	0005840	cellular_component	ribosome
g	0006412	biological_process	translation
g	1990904	cellular_component	ribonucleoprotein complex
h	0003735	molecular_function	structural constituent of ribosome
h	0005737	cellular_component	cytoplasm
h	0005840	cellular_component	ribosome
h	0006412	biological_process	translation
h	0008270	molecular_function	zinc ion binding
h	0022626	cellular_component	cytosolic ribosome
h	0046872	molecular_function	metal ion binding
h	1990904	cellular_component	ribonucleoprotein complex
i	0002181	biological_process	cytoplasmic translation
i	0003735	molecular_function	structural constituent of ribosome
i	0005737	cellular_component	cytoplasm
i	0005840	cellular_component	ribosome
i	0006412	biological_process	translation
i	0022625	cellular_component	cytosolic large ribosomal subunit
i	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue YMZ A 3801

Chain	Residue
2	ASN6
2	ALA7
2	PRO44
2	VAL50
A	A1476
A	A1479
A	A1503
F	TYR290

site_id	AC2
Number of Residues	3
Details	binding site for residue MG A 3802

Chain	Residue
A	C1442
K	YMZ301
A	G1441

site_id	AC3
Number of Residues	2
Details	binding site for residue MG A 3804

Chain	Residue
A	A1584
A	C1586

site_id	AC4
Number of Residues	2
Details	binding site for residue MG A 3806

Chain	Residue
A	C726
A	G2669

site_id	AC5
Number of Residues	4
Details	binding site for residue MG A 3808

Chain	Residue
8	ASP39
A	U720
A	A723
A	A1271

site_id	AC6
Number of Residues	1
Details	binding site for residue MG A 3809

Chain	Residue
A	C1269

site_id	AC7
Number of Residues	1
Details	binding site for residue MG A 3810

Chain	Residue
A	C923

site_id	AC8
Number of Residues	2
Details	binding site for residue MG A 3811

Chain	Residue
A	C719
A	U1061

site_id	AC9
Number of Residues	3
Details	binding site for residue MG A 3812

Chain	Residue
A	U2701
A	C2955
A	U2956

site_id	AD1
Number of Residues	1
Details	binding site for residue MG A 3813

Chain	Residue
A	C1080

site_id	AD2
Number of Residues	1
Details	binding site for residue MG A 3814

Chain	Residue
A	A40

site_id	AD3
Number of Residues	4
Details	binding site for residue MG A 3815

Chain	Residue
A	G41
A	C42
A	U2704
A	G2705

site_id	AD4
Number of Residues	2
Details	binding site for residue MG A 3817

Chain	Residue
A	U2709
A	G2946

site_id	AD5
Number of Residues	2
Details	binding site for residue MG A 3818

Chain	Residue
A	G1035
A	G3316

site_id	AD6
Number of Residues	3
Details	binding site for residue MG A 3819

Chain	Residue
A	A1034
A	G1035
A	A3317

site_id	AD7
Number of Residues	1
Details	binding site for residue MG A 3820

Chain	Residue
A	C2425

site_id	AD8
Number of Residues	1
Details	binding site for residue MG A 3821

Chain	Residue
A	C2439

site_id	AD9
Number of Residues	1
Details	binding site for residue MG A 3822

Chain	Residue
A	A2481

site_id	AE1
Number of Residues	2
Details	binding site for residue MG A 3823

Chain	Residue
A	A2536
A	A2606

site_id	AE2
Number of Residues	1
Details	binding site for residue MG A 3824

Chain	Residue
A	G2478

site_id	AE3
Number of Residues	1
Details	binding site for residue MG A 3825

Chain	Residue
A	U749

site_id	AE4
Number of Residues	2
Details	binding site for residue MG A 3826

Chain	Residue
A	A62
A	A63

site_id	AE5
Number of Residues	2
Details	binding site for residue MG A 3827

Chain	Residue
A	C1568
A	A1569

site_id	AE6
Number of Residues	3
Details	binding site for residue MG A 3828

Chain	Residue
A	G1069
A	A1515
A	G1516

site_id	AE7
Number of Residues	3
Details	binding site for residue MG A 3829

Chain	Residue
A	U1067
A	A1515
A	G1516

site_id	AE8
Number of Residues	4
Details	binding site for residue MG A 3830

Chain	Residue
A	G3175
A	A3176
A	C3226
A	U3227

site_id	AE9
Number of Residues	3
Details	binding site for residue MG A 3831

Chain	Residue
A	G3309
A	G3310
A	G3311

site_id	AF1
Number of Residues	3
Details	binding site for residue MG A 3832

Chain	Residue
A	C2622
A	A3278
A	U3279

site_id	AF2
Number of Residues	4
Details	binding site for residue MG A 3833

Chain	Residue
A	A2169
A	G2170
A	U2171
A	A3278

site_id	AF3
Number of Residues	1
Details	binding site for residue MG A 3834

Chain	Residue
A	A1729

site_id	AF4
Number of Residues	2
Details	binding site for residue MG A 3835

Chain	Residue
A	C1681
A	A1729

site_id	AF5
Number of Residues	2
Details	binding site for residue MG A 3836

Chain	Residue
A	G1733
A	G1735

site_id	AF6
Number of Residues	1
Details	binding site for residue MG A 3837

Chain	Residue
A	A1972

site_id	AF7
Number of Residues	1
Details	binding site for residue MG A 3838

Chain	Residue
A	C2116

site_id	AF8
Number of Residues	2
Details	binding site for residue MG A 3839

Chain	Residue
A	A2146
A	A2147

site_id	AF9
Number of Residues	3
Details	binding site for residue MG A 3840

Chain	Residue
A	U1657
A	G1658
A	A2146

site_id	AG1
Number of Residues	3
Details	binding site for residue MG A 3841

Chain	Residue
A	U1657
A	G1658
A	A1659

site_id	AG2
Number of Residues	1
Details	binding site for residue MG A 3842

Chain	Residue
A	U1117

site_id	AG3
Number of Residues	1
Details	binding site for residue MG A 3843

Chain	Residue
A	G1119

site_id	AG4
Number of Residues	4
Details	binding site for residue MG A 3844

Chain	Residue
A	A2975
A	A2976
A	U2977
A	U2979

site_id	AG5
Number of Residues	2
Details	binding site for residue MG A 3845

Chain	Residue
A	G3002
A	A3043

site_id	AG6
Number of Residues	2
Details	binding site for residue MG A 3848

Chain	Residue
A	A713
A	U2672

site_id	AG7
Number of Residues	2
Details	binding site for residue MG A 3849

Chain	Residue
A	A713
A	C714

site_id	AG8
Number of Residues	1
Details	binding site for residue MG A 3850

Chain	Residue
A	U1301

site_id	AG9
Number of Residues	2
Details	binding site for residue MG A 3851

Chain	Residue
A	U1279
A	A1278

site_id	AH1
Number of Residues	1
Details	binding site for residue MG A 3852

Chain	Residue
A	A1298

site_id	AH2
Number of Residues	6
Details	binding site for residue MG A 3853

Chain	Residue
A	C1303
A	C1304
A	U1305
A	A1306
A	A1307
K	LYS24

site_id	AH3
Number of Residues	2
Details	binding site for residue MG A 3854

Chain	Residue
A	U1296
A	C1456

site_id	AH4
Number of Residues	3
Details	binding site for residue MG A 3855

Chain	Residue
A	C273
A	G274
A	A325

site_id	AH5
Number of Residues	3
Details	binding site for residue MG A 3857

Chain	Residue
A	A227
A	U1538
A	A1566

site_id	AH6
Number of Residues	2
Details	binding site for residue MG A 3858

Chain	Residue
A	G379
A	A1566

site_id	AH7
Number of Residues	1
Details	binding site for residue MG A 3859

Chain	Residue
A	A2679

site_id	AH8
Number of Residues	2
Details	binding site for residue MG A 3860

Chain	Residue
A	A2526
A	G2527

site_id	AH9
Number of Residues	1
Details	binding site for residue MG A 3861

Chain	Residue
A	G3233

site_id	AI1
Number of Residues	3
Details	binding site for residue MG A 3862

Chain	Residue
A	A2691
A	U3232
A	G3233

site_id	AI2
Number of Residues	3
Details	binding site for residue MG A 3863

Chain	Residue
A	G2686
A	G2688
A	A3341

site_id	AI3
Number of Residues	4
Details	binding site for residue MG A 3864

Chain	Residue
A	G2687
A	G2688
A	G3304
A	A3305

site_id	AI4
Number of Residues	1
Details	binding site for residue MG A 3866

Chain	Residue
A	A3246

site_id	AI5
Number of Residues	2
Details	binding site for residue MG A 3867

Chain	Residue
A	U3440
A	MG3927

site_id	AI6
Number of Residues	2
Details	binding site for residue MG A 3868

Chain	Residue
A	A3472
E	LYS361

site_id	AI7
Number of Residues	2
Details	binding site for residue MG A 3869

Chain	Residue
A	A3727
A	A3728

site_id	AI8
Number of Residues	3
Details	binding site for residue MG A 3870

Chain	Residue
A	G2696
A	C3229
A	G3230

site_id	AI9
Number of Residues	2
Details	binding site for residue MG A 3871

Chain	Residue
A	G3174
A	G3230

site_id	AJ1
Number of Residues	1
Details	binding site for residue MG A 3872

Chain	Residue
A	C1681

site_id	AJ2
Number of Residues	2
Details	binding site for residue MG A 3873

Chain	Residue
A	A1684
A	G1685

site_id	AJ3
Number of Residues	2
Details	binding site for residue MG A 3874

Chain	Residue
A	A936
A	C937

site_id	AJ4
Number of Residues	1
Details	binding site for residue MG A 3875

Chain	Residue
A	G941

site_id	AJ5
Number of Residues	2
Details	binding site for residue MG A 3876

Chain	Residue
A	A47
A	U49

site_id	AJ6
Number of Residues	1
Details	binding site for residue MG A 3877

Chain	Residue
A	U287

site_id	AJ7
Number of Residues	2
Details	binding site for residue MG A 3878

Chain	Residue
A	A1688
A	U1700

site_id	AJ8
Number of Residues	4
Details	binding site for residue MG A 3879

Chain	Residue
A	G641
A	A642
A	G643
A	G644

site_id	AJ9
Number of Residues	1
Details	binding site for residue MG A 3880

Chain	Residue
A	A2176

site_id	AK1
Number of Residues	1
Details	binding site for residue MG A 3881

Chain	Residue
A	G994

site_id	AK2
Number of Residues	6
Details	binding site for residue MG A 3882

Chain	Residue
A	U3186
A	G3187
A	U3188
A	G3189
A	G3190
A	U3217

site_id	AK3
Number of Residues	2
Details	binding site for residue MG A 3883

Chain	Residue
A	U3188
A	G3190

site_id	AK4
Number of Residues	2
Details	binding site for residue MG A 3886

Chain	Residue
A	A3261
A	A3262

site_id	AK5
Number of Residues	2
Details	binding site for residue MG A 3887

Chain	Residue
A	G2170
A	U2171

site_id	AK6
Number of Residues	3
Details	binding site for residue MG A 3888

Chain	Residue
A	G3233
A	G3304
A	U3339

site_id	AK7
Number of Residues	2
Details	binding site for residue MG A 3889

Chain	Residue
A	A3315
A	G3316

site_id	AK8
Number of Residues	2
Details	binding site for residue MG A 3890

Chain	Residue
A	G1337
A	U1338

site_id	AK9
Number of Residues	2
Details	binding site for residue MG A 3891

Chain	Residue
A	G3697
A	A3768

site_id	AL1
Number of Residues	2
Details	binding site for residue MG A 3892

Chain	Residue
A	U1038
A	U1041

site_id	AL2
Number of Residues	3
Details	binding site for residue MG A 3893

Chain	Residue
A	A2431
A	U2433
A	U2434

site_id	AL3
Number of Residues	2
Details	binding site for residue MG A 3894

Chain	Residue
A	U1644
A	C1665

site_id	AL4
Number of Residues	2
Details	binding site for residue MG A 3895

Chain	Residue
A	G1640
e	GLY2

site_id	AL5
Number of Residues	2
Details	binding site for residue MG A 3896

Chain	Residue
A	G1634
A	G1635

site_id	AL6
Number of Residues	4
Details	binding site for residue MG A 3897

Chain	Residue
A	G1637
A	A1748
A	A2102
A	C2103

site_id	AL7
Number of Residues	2
Details	binding site for residue MG A 3898

Chain	Residue
A	U1747
A	C2103

site_id	AL8
Number of Residues	1
Details	binding site for residue MG A 3899

Chain	Residue
A	G33

site_id	AL9
Number of Residues	1
Details	binding site for residue MG A 3900

Chain	Residue
A	A52

site_id	AM1
Number of Residues	2
Details	binding site for residue MG A 3901

Chain	Residue
A	G22
A	G56

site_id	AM2
Number of Residues	2
Details	binding site for residue MG A 3902

Chain	Residue
A	A925
A	U1053

site_id	AM3
Number of Residues	3
Details	binding site for residue MG A 3903

Chain	Residue
A	G3182
A	U3219
A	U3220

site_id	AM4
Number of Residues	1
Details	binding site for residue MG A 3904

Chain	Residue
A	G976

site_id	AM5
Number of Residues	2
Details	binding site for residue MG A 3905

Chain	Residue
A	G2427
A	A2617

site_id	AM6
Number of Residues	2
Details	binding site for residue MG A 3906

Chain	Residue
A	G2696
A	A2697

site_id	AM7
Number of Residues	2
Details	binding site for residue MG A 3907

Chain	Residue
A	U1058
A	A3176

site_id	AM8
Number of Residues	2
Details	binding site for residue MG A 3908

Chain	Residue
A	G366
A	G2112

site_id	AM9
Number of Residues	2
Details	binding site for residue MG A 3909

Chain	Residue
A	C2111
e	LYS48

site_id	AN1
Number of Residues	3
Details	binding site for residue MG A 3910

Chain	Residue
A	G86
A	G795
A	C796

site_id	AN2
Number of Residues	2
Details	binding site for residue MG A 3911

Chain	Residue
A	A1582
A	G1583

site_id	AN3
Number of Residues	2
Details	binding site for residue MG A 3912

Chain	Residue
A	G730
A	A2654

site_id	AN4
Number of Residues	4
Details	binding site for residue MG A 3913

Chain	Residue
A	U408
A	A409
A	G416
A	G1564

site_id	AN5
Number of Residues	1
Details	binding site for residue MG A 3914

Chain	Residue
A	A2572

site_id	AN6
Number of Residues	2
Details	binding site for residue MG A 3915

Chain	Residue
A	G736
A	C1581

site_id	AN7
Number of Residues	1
Details	binding site for residue MG A 3916

Chain	Residue
A	A1518

site_id	AN8
Number of Residues	2
Details	binding site for residue MG A 3917

Chain	Residue
A	U1061
A	G1583

site_id	AN9
Number of Residues	3
Details	binding site for residue MG A 3918

Chain	Residue
8	ASP39
A	U718
A	A723

site_id	AO1
Number of Residues	4
Details	binding site for residue MG A 3919

Chain	Residue
A	U720
A	G722
A	A3176
A	U3227

site_id	AO2
Number of Residues	1
Details	binding site for residue MG A 3920

Chain	Residue
A	G1082

site_id	AO3
Number of Residues	5
Details	binding site for residue MG A 3921

Chain	Residue
A	A2440
A	U2441
A	G2480
D	LYS198
D	ARG200

site_id	AO4
Number of Residues	1
Details	binding site for residue MG A 3922

Chain	Residue
A	C3318

site_id	AO5
Number of Residues	2
Details	binding site for residue MG A 3923

Chain	Residue
A	G2608
D	GLN217

site_id	AO6
Number of Residues	1
Details	binding site for residue MG A 3924

Chain	Residue
A	U2567

site_id	AO7
Number of Residues	3
Details	binding site for residue MG A 3925

Chain	Residue
A	G2566
A	G2604
A	U3321

site_id	AO8
Number of Residues	4
Details	binding site for residue MG A 3926

Chain	Residue
A	A989
A	U990
A	U2434
A	A2435

site_id	AO9
Number of Residues	4
Details	binding site for residue MG A 3927

Chain	Residue
A	G3439
A	U3440
A	G3473
A	MG3867

site_id	AP1
Number of Residues	2
Details	binding site for residue MG A 3928

Chain	Residue
A	A2164
A	G2165

site_id	AP2
Number of Residues	3
Details	binding site for residue MG A 3929

Chain	Residue
A	A1673
A	U2101
Y	VAL160

site_id	AP3
Number of Residues	2
Details	binding site for residue MG A 3930

Chain	Residue
A	C1676
A	G1677

site_id	AP4
Number of Residues	4
Details	binding site for residue MG A 3931

Chain	Residue
A	A727
A	C728
A	A3231
A	U3232

site_id	AP5
Number of Residues	3
Details	binding site for residue MG A 3932

Chain	Residue
A	A935
A	A936
c	GLN33

site_id	AP6
Number of Residues	2
Details	binding site for residue MG A 3933

Chain	Residue
A	U1604
A	U1628

site_id	AP7
Number of Residues	1
Details	binding site for residue MG A 3934

Chain	Residue
A	G997

site_id	AP8
Number of Residues	2
Details	binding site for residue MG A 3935

Chain	Residue
A	C1627
A	U2138

site_id	AP9
Number of Residues	4
Details	binding site for residue MG A 3936

Chain	Residue
A	C1627
A	U1628
A	G1629
A	U2138

site_id	AQ1
Number of Residues	2
Details	binding site for residue MG A 3937

Chain	Residue
A	A738
A	U1579

site_id	AQ2
Number of Residues	1
Details	binding site for residue MG A 3938

Chain	Residue
A	U1117

site_id	AQ3
Number of Residues	3
Details	binding site for residue MG A 3939

Chain	Residue
A	A39
A	G41
A	C42

site_id	AQ4
Number of Residues	2
Details	binding site for residue MG A 3940

Chain	Residue
A	A2706
A	U2950

site_id	AQ5
Number of Residues	1
Details	binding site for residue MG A 3941

Chain	Residue
A	A2706

site_id	AQ6
Number of Residues	2
Details	binding site for residue MG A 3942

Chain	Residue
A	A58
C	G38

site_id	AQ7
Number of Residues	2
Details	binding site for residue MG A 3943

Chain	Residue
A	A63
A	C329

site_id	AQ8
Number of Residues	1
Details	binding site for residue MG A 3944

Chain	Residue
A	A70

site_id	AQ9
Number of Residues	2
Details	binding site for residue MG A 3945

Chain	Residue
A	G353
A	A356

site_id	AR1
Number of Residues	2
Details	binding site for residue MG A 3946

Chain	Residue
A	G353
A	A355

site_id	AR2
Number of Residues	4
Details	binding site for residue MG A 3947

Chain	Residue
A	C413
A	C414
A	U415
A	G416

site_id	AR3
Number of Residues	3
Details	binding site for residue MG A 3948

Chain	Residue
A	A608
A	C609
A	G611

site_id	AR4
Number of Residues	2
Details	binding site for residue MG A 3950

Chain	Residue
A	C3248
A	A3249

site_id	AR5
Number of Residues	1
Details	binding site for residue MG A 3951

Chain	Residue
A	U83

site_id	AR6
Number of Residues	1
Details	binding site for residue MG A 3952

Chain	Residue
A	G1540

site_id	AR7
Number of Residues	1
Details	binding site for residue MG A 3953

Chain	Residue
A	A2660

site_id	AR8
Number of Residues	3
Details	binding site for residue MG A 3954

Chain	Residue
A	U1645
A	C1646
A	A1663

site_id	AR9
Number of Residues	3
Details	binding site for residue MG A 3956

Chain	Residue
A	G1254
A	G1255
Q	ASN14

site_id	AS1
Number of Residues	2
Details	binding site for residue MG B 201

Chain	Residue
A	U1285
B	G83

site_id	AS2
Number of Residues	3
Details	binding site for residue MG B 202

Chain	Residue
B	G21
B	A54
B	A55

site_id	AS3
Number of Residues	1
Details	binding site for residue MG B 203

Chain	Residue
B	G65

site_id	AS4
Number of Residues	3
Details	binding site for residue MG C 201

Chain	Residue
A	G1528
A	A1569
C	U24

site_id	AS5
Number of Residues	1
Details	binding site for residue MG C 202

Chain	Residue
C	U109

site_id	AS6
Number of Residues	1
Details	binding site for residue MG C 203

Chain	Residue
C	A91

site_id	AS7
Number of Residues	1
Details	binding site for residue MG C 204

Chain	Residue
C	A69

site_id	AS8
Number of Residues	2
Details	binding site for residue MG C 205

Chain	Residue
C	A7
C	G8

site_id	AS9
Number of Residues	14
Details	binding site for residue YMZ K 301

Chain	Residue
A	G1435
A	C1440
A	G1441
A	MG3802
K	LEU15
K	ILE42
K	ASN49
K	LYS52
K	TYR53
K	GLU55
K	PHE56
K	ILE78
K	ARG81
K	LEU140

site_id	AT1
Number of Residues	2
Details	binding site for residue MG M 201

Chain	Residue
A	G3276
M	ASN49

site_id	AT2
Number of Residues	5
Details	binding site for residue ZN a 201

Chain	Residue
a	CYS44
a	CYS47
a	THR49
a	CYS81
a	CYS84

site_id	AT3
Number of Residues	4
Details	binding site for residue ZN c 101

Chain	Residue
c	CYS22
c	CYS25
c	CYS37
c	CYS40

site_id	AT4
Number of Residues	4
Details	binding site for residue ZN f 101

Chain	Residue
f	CYS20
f	CYS23
f	CYS34
f	CYS39

site_id	AT5
Number of Residues	4
Details	binding site for residue ZN h 101

Chain	Residue
h	CYS39
h	CYS42
h	CYS57
h	CYS60

site_id	AT6
Number of Residues	5
Details	binding site for residue ZN i 201

Chain	Residue
i	CYS12
i	ASN14
i	CYS16
i	CYS73
i	CYS76

Functional Information from PROSITE/UniProt

site_id	PS00050
Number of Residues	16
Details	RIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYVRLSgehdaleV

Chain	Residue	Details
Y	LYS168-VAL183

site_id	PS00051
Number of Residues	17
Details	RIBOSOMAL_L39E Ribosomal protein L39e signature. KKdtkIryNtkrRHWRR

Chain	Residue	Details
e	LYS30-ARG46

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD

Chain	Residue	Details
f	LYS-49-ASP-24

site_id	PS00467
Number of Residues	12
Details	RIBOSOMAL_L2 Ribosomal protein L2 signature. PkvRGVAmNPvE

Chain	Residue	Details
D	PRO197-GLU208

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FnpnemiDviSvTkGHGtkGvvsR

Chain	Residue	Details
E	PHE206-ARG229

site_id	PS00475
Number of Residues	33
Details	RIBOSOMAL_L15 Ribosomal protein L15 signature. KVLGnGkLkhnqpIvVkaryFSsvAekkIkavG

Chain	Residue	Details
O	LYS109-GLY141

site_id	PS00580
Number of Residues	21
Details	RIBOSOMAL_L32E Ribosomal protein L32e signature. FtRfqsnRfmRVkpa..WRKprG

Chain	Residue	Details
8	PHE17-GLY37

site_id	PS00709
Number of Residues	25
Details	RIBOSOMAL_L30E_1 Ribosomal protein L30e signature 1. SgkyqfGrKscLKalRtGkgKlVIV

Chain	Residue	Details
6	SER23-VAL47

site_id	PS00993
Number of Residues	21
Details	RIBOSOMAL_L30E_2 Ribosomal protein L30e signature 2. DLGTacGKlfriscLvItDvG

Chain	Residue	Details
6	ASP79-GLY99

site_id	PS01077
Number of Residues	20
Details	RIBOSOMAL_L37E Ribosomal protein L37e signature. GTgSfGkRngkt.HflClRCG

Chain	Residue	Details
c	GLY7-GLY26

site_id	PS01104
Number of Residues	15
Details	RIBOSOMAL_L13E Ribosomal protein L13e signature. RlGKGFTFeELkgaG

Chain	Residue	Details
L	ARG69-GLY83

site_id	PS01106
Number of Residues	18
Details	RIBOSOMAL_L18E Ribosomal protein L18e signature. KrLimPKryRPpLSLsKL

Chain	Residue	Details
S	LYS50-LEU67

site_id	PS01144
Number of Residues	15
Details	RIBOSOMAL_L31E Ribosomal protein L31e signature. VRLDvkLNkFiWsKG

Chain	Residue	Details
7	VAL57-GLY71

site_id	PS01145
Number of Residues	14
Details	RIBOSOMAL_L34E Ribosomal protein L34e signature. TkSnKvrpvRTPGG

Chain	Residue	Details
a	THR15-GLY28

site_id	PS01171
Number of Residues	26
Details	RIBOSOMAL_L21E Ribosomal protein L21e signature. GDyVdivcdstqqk.GmpFnyYhGkTG

Chain	Residue	Details
V	GLY38-GLY63

site_id	PS01172
Number of Residues	12
Details	RIBOSOMAL_L44E Ribosomal protein L44e signature. KtTKKivLKleC

Chain	Residue	Details
i	LYS62-CYS73

site_id	PS01190
Number of Residues	11
Details	RIBOSOMAL_L36E Ribosomal protein L36e signature. PYEKRiIELIK

Chain	Residue	Details
b	PRO56-LYS66

site_id	PS01194
Number of Residues	24
Details	RIBOSOMAL_L15E Ribosomal protein L15e signature. DKARrLGYkAiqGFVIYRvRVrRG

Chain	Residue	Details
P	ASP46-GLY69

site_id	PS01257
Number of Residues	22
Details	RIBOSOMAL_L10E Ribosomal protein L10e signature. ADRlqtGMRgAFGKPnGvvARV

Chain	Residue	Details
Q	ALA108-VAL129

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI16
Number of Residues	21
Details	Zinc finger: {"description":"C4-type"}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)