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5UM3

Crystal structure of the V122L mutant of human UBR-box domain from UBR2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
E3 ubiquitin-protein ligase UBR2polymer758251.41UniProt (Q8IWV8)
Pfam (PF02207)
Homo sapiens (Human)N-recognin-2,RING-type E3 ubiquitin transferase UBR2,Ubiquitin-protein ligase E3-alpha-2,Ubiquitin-protein ligase E3-alpha-II
2B, C, D
(A)
ZINC IONnon-polymer65.43Chemie (ZN)
3E
(A)
waterwater18.092Chemie (HOH)
Sequence modifications
A: 98 - 167 (UniProt: Q8IWV8)
PDBExternal DatabaseDetails
Gly 93-expression tag
Pro 94-expression tag
Leu 95-expression tag
Gly 96-expression tag
Ser 97-expression tag
Leu 122Val 122engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight8251.4
Non-Polymers*Number of molecules3
Total formula weight196.2
All*Total formula weight8447.6
*Water molecules are not included.

238582

PDB entries from 2025-07-09

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