5UM3
Crystal structure of the V122L mutant of human UBR-box domain from UBR2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | E3 ubiquitin-protein ligase UBR2 | polymer | 75 | 8251.4 | 1 | UniProt (Q8IWV8) Pfam (PF02207) | Homo sapiens (Human) | N-recognin-2,RING-type E3 ubiquitin transferase UBR2,Ubiquitin-protein ligase E3-alpha-2,Ubiquitin-protein ligase E3-alpha-II |
| 2 | B, C, D (A) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 3 | E (A) | water | water | 18.0 | 92 | Chemie (HOH) |
Sequence modifications
A: 98 - 167 (UniProt: Q8IWV8)
| PDB | External Database | Details |
|---|---|---|
| Gly 93 | - | expression tag |
| Pro 94 | - | expression tag |
| Leu 95 | - | expression tag |
| Gly 96 | - | expression tag |
| Ser 97 | - | expression tag |
| Leu 122 | Val 122 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 8251.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 196.2 | |
| All* | Total formula weight | 8447.6 |
