5UE2
proMMP-7 with heparin octasaccharide bridging between domains
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Matrilysin | polymer | 247 | 27589.1 | 1 | UniProt (P09237) Pfam (PF01471) Pfam (PF00413) | Homo sapiens (Human) | Matrin,Matrix metalloproteinase-7,MMP-7,Pump-1 protease,Uterine metalloproteinase |
| 2 | B (B) | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose | branched | 2327.9 | 1 | In PDB GlyTouCan (G40559JB) | |||
| 3 | C, D (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 4 | E, F (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
A: 1 - 247 (UniProt: P09237)
| PDB | External Database | Details |
|---|---|---|
| Ala 195 | Glu 215 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27589.1 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 2327.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 211.0 | |
| All* | Total formula weight | 30128.0 |
