5UE2

proMMP-7 with heparin octasaccharide bridging between domains

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004175	molecular_function	endopeptidase activity
A	0004222	molecular_function	metalloendopeptidase activity
A	0004252	molecular_function	serine-type endopeptidase activity
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0006508	biological_process	proteolysis
A	0006509	biological_process	membrane protein ectodomain proteolysis
A	0008233	molecular_function	peptidase activity
A	0008237	molecular_function	metallopeptidase activity
A	0008270	molecular_function	zinc ion binding
A	0016787	molecular_function	hydrolase activity
A	0022617	biological_process	extracellular matrix disassembly
A	0030198	biological_process	extracellular matrix organization
A	0030335	biological_process	positive regulation of cell migration
A	0030574	biological_process	collagen catabolic process
A	0031012	cellular_component	extracellular matrix
A	0031293	biological_process	membrane protein intracellular domain proteolysis
A	0046872	molecular_function	metal ion binding
A	0070062	cellular_component	extracellular exosome

Functional Information from PROSITE/UniProt

site_id	PS00546
Number of Residues	8
Details	CYSTEINE_SWITCH Matrixins cysteine switch. PRCGvPDV

Chain	Residue	Details
A	PRO65-VAL72

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	Motif: {"description":"Cysteine switch","evidences":[{"evidenceCode":"ECO:0000250"}]}

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {}

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"description":"in inhibited form","evidences":[{"evidenceCode":"ECO:0000250"}]}

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site_id	SWS_FT_FI4
Number of Residues	17
Details	Binding site: {}

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