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5UE2

proMMP-7 with heparin octasaccharide bridging between domains

Functional Information from GO Data
ChainGOidnamespacecontents
A0002779biological_processantibacterial peptide secretion
A0002780biological_processantibacterial peptide biosynthetic process
A0004175molecular_functionendopeptidase activity
A0004222molecular_functionmetalloendopeptidase activity
A0004252molecular_functionserine-type endopeptidase activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0006508biological_processproteolysis
A0006509biological_processmembrane protein ectodomain proteolysis
A0008233molecular_functionpeptidase activity
A0008237molecular_functionmetallopeptidase activity
A0008270molecular_functionzinc ion binding
A0009410biological_processresponse to xenobiotic stimulus
A0022617biological_processextracellular matrix disassembly
A0030198biological_processextracellular matrix organization
A0030335biological_processpositive regulation of cell migration
A0030574biological_processcollagen catabolic process
A0031012cellular_componentextracellular matrix
A0031293biological_processmembrane protein intracellular domain proteolysis
A0042127biological_processregulation of cell population proliferation
A0042742biological_processdefense response to bacterium
A0046872molecular_functionmetal ion binding
A0050829biological_processdefense response to Gram-negative bacterium
A0050830biological_processdefense response to Gram-positive bacterium
A0070062cellular_componentextracellular exosome
Functional Information from PROSITE/UniProt
site_idPS00546
Number of Residues8
DetailsCYSTEINE_SWITCH Matrixins cysteine switch. PRCGvPDV
ChainResidueDetails
APRO65-VAL72

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE:
ChainResidueDetails
AALA195

site_idSWS_FT_FI2
Number of Residues1
DetailsBINDING: in inhibited form => ECO:0000250
ChainResidueDetails
ACYS67

site_idSWS_FT_FI3
Number of Residues17
DetailsBINDING:
ChainResidueDetails
AASP133
AGLY167
AASP169
AHIS171
AASP173
AGLU176
AHIS194
AHIS198
AHIS204
AHIS143
AASP145
AASP150
AGLY151
AGLY153
ATHR155
AHIS158
AGLY165

219140

PDB entries from 2024-05-01

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