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5UCJ

Hsp90b N-terminal domain with inhibitors

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DHeat shock protein HSP 90-betapolymer22024582.74UniProt (P08238)
Pfam (PF13589)
In PDB
Homo sapiens (Human)HSP 90,Heat shock 84 kDa,HSP84
2A, B, C, D(5-fluoroisoindolin-2-yl)(4-hydroxy-5-isopropylbenzo[d]isoxazol-7-yl)methanonenon-polymer340.34Chemie (KU3)
3A, B, C, DDIMETHYL SULFOXIDEnon-polymer78.16Chemie (DMS)
4waterwater18.0661Chemie (HOH)
Sequence modifications
A, B, C, D: 1 - 218 (UniProt: P08238)
PDBExternal DatabaseDetails
Gly -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight98331.0
Non-Polymers*Number of molecules10
Total formula weight1830.2
All*Total formula weight100161.1
*Water molecules are not included.

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PDB entries from 2024-04-24

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