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5UC4

Hsp90b N-terminal domain with inhibitors

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Heat shock protein HSP 90-betapolymer22024582.74UniProt (P08238)
Pfam (PF13589)
Homo sapiens (Human)HSP 90,Heat shock 84 kDa,HSP84
2E, H, J, M
(A, B, C, D)
5-Hydroxy-4-(isoindoline-2-carbonyl)-2-isopropylbenzaldehydenon-polymer309.44Chemie (83S)
3F, K
(A, C)
GLYCEROLnon-polymer92.12Chemie (GOL)
4G, I, L, N
(A, B, C, D)
DIMETHYL SULFOXIDEnon-polymer78.14Chemie (DMS)
5O, P, Q, R
(A, B, C, D)
waterwater18.0507Chemie (HOH)
Sequence modifications
A, B, C, D: 1 - 218 (UniProt: P08238)
PDBExternal DatabaseDetails
Gly -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight98331.0
Non-Polymers*Number of molecules10
Total formula weight1734.2
All*Total formula weight100065.1
*Water molecules are not included.

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PDB entries from 2025-06-25

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