Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006457 | biological_process | protein folding |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| A | 0051082 | molecular_function | unfolded protein binding |
| A | 0140662 | molecular_function | ATP-dependent protein folding chaperone |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006457 | biological_process | protein folding |
| B | 0016887 | molecular_function | ATP hydrolysis activity |
| B | 0051082 | molecular_function | unfolded protein binding |
| B | 0140662 | molecular_function | ATP-dependent protein folding chaperone |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006457 | biological_process | protein folding |
| C | 0016887 | molecular_function | ATP hydrolysis activity |
| C | 0051082 | molecular_function | unfolded protein binding |
| C | 0140662 | molecular_function | ATP-dependent protein folding chaperone |
| D | 0005524 | molecular_function | ATP binding |
| D | 0006457 | biological_process | protein folding |
| D | 0016887 | molecular_function | ATP hydrolysis activity |
| D | 0051082 | molecular_function | unfolded protein binding |
| D | 0140662 | molecular_function | ATP-dependent protein folding chaperone |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue 83S A 301 |
| Chain | Residue |
| A | LEU43 |
| A | THR179 |
| A | VAL181 |
| A | DMS303 |
| A | HOH480 |
| A | ASN46 |
| A | ASP49 |
| A | ALA50 |
| A | ASP88 |
| A | ILE91 |
| A | GLY92 |
| A | MET93 |
| A | PHE133 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 302 |
| Chain | Residue |
| A | ALA16 |
| A | PHE17 |
| A | GLN18 |
| A | ALA19 |
| D | ALA16 |
| D | PHE17 |
| D | GLN18 |
| D | ALA19 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 303 |
| Chain | Residue |
| A | ASN101 |
| A | ALA106 |
| A | GLY130 |
| A | TYR134 |
| A | 83S301 |
| A | HOH403 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | binding site for residue 83S B 301 |
| Chain | Residue |
| B | LEU43 |
| B | ASN46 |
| B | ASP49 |
| B | ALA50 |
| B | ASP88 |
| B | ILE91 |
| B | GLY92 |
| B | PHE133 |
| B | THR179 |
| B | VAL181 |
| B | DMS302 |
| B | HOH435 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue DMS B 302 |
| Chain | Residue |
| B | ASN101 |
| B | ALA106 |
| B | GLY130 |
| B | VAL131 |
| B | TYR134 |
| B | 83S301 |
| B | HOH431 |
| site_id | AC6 |
| Number of Residues | 11 |
| Details | binding site for residue 83S C 301 |
| Chain | Residue |
| C | LEU43 |
| C | ASN46 |
| C | ALA50 |
| C | ASP88 |
| C | ILE91 |
| C | GLY92 |
| C | PHE133 |
| C | THR179 |
| C | VAL181 |
| C | DMS303 |
| C | HOH431 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | binding site for residue GOL C 302 |
| Chain | Residue |
| B | ALA16 |
| B | PHE17 |
| B | GLN18 |
| B | ALA19 |
| C | ALA16 |
| C | PHE17 |
| C | GLN18 |
| C | ALA19 |
| C | HOH425 |
| C | HOH493 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue DMS C 303 |
| Chain | Residue |
| C | ASN101 |
| C | ALA106 |
| C | GLY130 |
| C | VAL131 |
| C | TYR134 |
| C | 83S301 |
| C | HOH406 |
| site_id | AC9 |
| Number of Residues | 11 |
| Details | binding site for residue 83S D 301 |
| Chain | Residue |
| D | LEU43 |
| D | ASN46 |
| D | ALA50 |
| D | ASP88 |
| D | ILE91 |
| D | GLY92 |
| D | MET93 |
| D | PHE133 |
| D | THR179 |
| D | VAL181 |
| D | HOH427 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue DMS D 302 |
| Chain | Residue |
| D | ASN101 |
| D | GLY130 |
| D | TYR134 |
| D | HOH458 |
| D | HOH508 |
Functional Information from PROSITE/UniProt
| site_id | PS00298 |
| Number of Residues | 10 |
| Details | HSP90 Heat shock hsp90 proteins family signature. YsNKEIFLRE |
| Chain | Residue | Details |
| A | TYR33-GLU42 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 424 |
| Details | Region: {"description":"Interaction with BIRC2","evidences":[{"source":"PubMed","id":"25486457","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Site: {"description":"Cleaved under oxidative stress","evidences":[{"source":"PubMed","id":"22848402","evidenceCode":"ECO:0000269"}]} |
