5U86
Structure of the Aquifex aeolicus LpxC/LPC-069 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | UDP-3-O-acyl-N-acetylglucosamine deacetylase | polymer | 275 | 31453.0 | 1 | UniProt (O67648) Pfam (PF03331) | Aquifex aeolicus (strain VF5) | UDP-3-O-acyl-GlcNAc deacetylase,UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | N-[(2S,3S)-4,4-difluoro-3-hydroxy-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]-4-({4-[(morpholin-4-yl)methyl]phenyl}ethynyl)benzamide | non-polymer | 487.5 | 1 | Chemie (81V) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | E, F (A) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 6 | G, H, I (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 7 | J (A) | water | water | 18.0 | 441 | Chemie (HOH) |
Sequence modifications
A: 1 - 275 (UniProt: O67648)
| PDB | External Database | Details |
|---|---|---|
| Ala 181 | Cys 181 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31453.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 964.5 | |
| All* | Total formula weight | 32417.5 |
