5U86
Structure of the Aquifex aeolicus LpxC/LPC-069 complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006796 | biological_process | phosphate-containing compound metabolic process |
| A | 0009245 | biological_process | lipid A biosynthetic process |
| A | 0016020 | cellular_component | membrane |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0019637 | biological_process | organophosphate metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0103117 | molecular_function | UDP-3-O-acyl-N-acetylglucosamine deacetylase activity |
| A | 1901135 | biological_process | carbohydrate derivative metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 301 |
| Chain | Residue |
| A | HIS74 |
| A | HIS226 |
| A | ASP230 |
| A | 81V302 |
| site_id | AC2 |
| Number of Residues | 23 |
| Details | binding site for residue 81V A 302 |
| Chain | Residue |
| A | PHE180 |
| A | ILE186 |
| A | GLY198 |
| A | SER199 |
| A | THR203 |
| A | VAL205 |
| A | TYR212 |
| A | HIS226 |
| A | LYS227 |
| A | ASP230 |
| A | HIS253 |
| A | ZN301 |
| A | PO4304 |
| A | HOH510 |
| A | HOH538 |
| A | HOH597 |
| A | HOH635 |
| A | HOH665 |
| A | ILE18 |
| A | HIS58 |
| A | GLU73 |
| A | HIS74 |
| A | THR179 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 303 |
| Chain | Residue |
| A | GLU127 |
| A | GLN267 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | binding site for residue PO4 A 304 |
| Chain | Residue |
| A | THR56 |
| A | HIS58 |
| A | LYS227 |
| A | GLY252 |
| A | HIS253 |
| A | 81V302 |
| A | HOH530 |
| A | HOH568 |
| A | HOH596 |
| A | HOH665 |
| A | HOH726 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue PO4 A 305 |
| Chain | Residue |
| A | ASN57 |
| A | HIS58 |
| A | PHE158 |
| A | HIS188 |
| A | HOH401 |
| A | HOH418 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 306 |
| Chain | Residue |
| A | ASP122 |
| A | TYR123 |
| A | PHE124 |
| A | SER240 |
| A | GLN267 |
| A | HOH486 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 307 |
| Chain | Residue |
| A | TYR45 |
| A | HOH430 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 308 |
| Chain | Residue |
| A | HOH447 |
| A | HOH454 |
| A | HOH529 |
| A | HOH614 |
| A | HOH677 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_00388","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15705580","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00388","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12819349","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15705580","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1P42","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YH8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YHC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
