5U1E
Crystal structure of a methyltransferase involved in the biosynthesis of gentamicin in complex with the kanamycin B
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Putative gentamicin methyltransferase | polymer | 341 | 37395.7 | 1 | UniProt (Q2MG72) | Micromonospora echinospora | |
| 2 | B (A) | (1R,2S,3S,4R,6S)-4,6-DIAMINO-3-[(3-AMINO-3-DEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-2-HYDROXYCYCLOHEXYL 2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSIDE | non-polymer | 483.5 | 1 | Chemie (9CS) PubChem (816) PubChem (71201) PubChem (9938209) PubChem (12305443) PubChem (12305444) PubChem (16667723) PubChem (16757757) PubChem (16758194) PubChem (20849273) PubChem (70683016) PubChem (71306482) PubChem (439318) PubChem (118912249) PubChem (133126454) PubChem (11698716) PubChem (58283955) PubChem (59062015) PubChem (162875361) PubChem (68312129) PubChem (68316021) PubChem (75358283) PubChem (89546223) PubChem (89563805) PubChem (91313054) PubChem (117650585) PubChem (117650609) PubChem (118517704) PubChem (118518941) PubChem (121343042) PubChem (134766950) PubChem (135020706) PubChem (162656574) PubChem (162875359) PubChem (162875360) PubChem (163964432) PubChem (173745808) PubChem (173973067) PubChem (175674194) | |||
| 3 | C (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) PubChem (193) PubChem (13792) PubChem (189149) PubChem (439155) PubChem (5284331) PubChem (71170554) PubChem (13231890) PubChem (16760024) PubChem (25210495) PubChem (44361184) PubChem (177678424) PubChem (46936206) PubChem (21125603) PubChem (25203782) PubChem (52224400) PubChem (50989525) PubChem (51380914) PubChem (52224398) PubChem (6419189) PubChem (57544532) PubChem (59046843) PubChem (59170628) PubChem (164157219) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (118374891) PubChem (118560068) PubChem (126969526) PubChem (129105892) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525) | |||
| 4 | D (A) | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence modifications
A: 1 - 321 (UniProt: Q2MG72)
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | initiating methionine |
| Gly -18 | - | expression tag |
| Ser -17 | - | expression tag |
| Ser -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37395.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 867.9 | |
| All* | Total formula weight | 38263.7 |
