5U1E
Crystal structure of a methyltransferase involved in the biosynthesis of gentamicin in complex with the kanamycin B
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0032259 | biological_process | methylation |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue 9CS A 401 |
| Chain | Residue |
| A | ASP95 |
| A | LEU208 |
| A | GLU209 |
| A | ASN235 |
| A | ARG281 |
| A | SAH402 |
| A | HOH516 |
| A | HOH573 |
| A | HOH582 |
| A | HOH584 |
| A | VAL96 |
| A | GLU98 |
| A | GLN101 |
| A | TRP110 |
| A | GLU111 |
| A | ASN194 |
| A | SER195 |
| A | ASN198 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | binding site for residue SAH A 402 |
| Chain | Residue |
| A | ASP107 |
| A | GLY131 |
| A | CYS132 |
| A | GLY133 |
| A | VAL136 |
| A | ASP152 |
| A | VAL153 |
| A | ASP179 |
| A | MET180 |
| A | ASN194 |
| A | LEU207 |
| A | LEU208 |
| A | ILE214 |
| A | 9CS401 |
| A | HOH513 |
| A | HOH529 |
| A | HOH538 |
| A | HOH539 |
| A | HOH542 |
| A | HOH545 |
| A | HOH580 |
