5U08
Crystal structure of an aminoglycoside acetyltransferase meta-AAC0020 from an uncultured soil metagenomic sample in complex with sisomicin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | aminoglycoside acetyltransferase meta-AAC0020 | polymer | 157 | 18434.9 | 4 | UniProt (A0A059WZ16) | uncultured bacterium | |
| 2 | E, H, M, Q (A, C, D) | (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside | non-polymer | 447.5 | 4 | Chemie (SIS) | |||
| 3 | F, S, T (A, D) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 4 | G, L, P, R (A, B, C, D) | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
| 5 | I, J, K, N, O (A, B, C) | CALCIUM ION | non-polymer | 40.1 | 5 | Chemie (CA) | |||
| 6 | U, V, W, X (A, B, C, D) | water | water | 18.0 | 971 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 157 (UniProt: A0A059WZ16)
| PDB | External Database | Details |
|---|---|---|
| Ala 138 | Tyr 138 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 73739.6 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2299.6 | |
| All* | Total formula weight | 76039.1 |
