5TWX
Crystal Structure of BRD9 bromodomain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Bromodomain-containing protein 9 | polymer | 121 | 13808.0 | 4 | UniProt (Q9H8M2) Pfam (PF00439) | Homo sapiens (Human) | Rhabdomyosarcoma antigen MU-RMS-40.8 |
| 2 | E, F, G, H (A, B, C, D) | N-[6-({2-[(3S)-2,6-dioxopiperidin-3-yl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}oxy)hexyl]-2-(4-{2-[N-(1,1-dioxo-1lambda~6~-thian-4-yl)carbamimidoyl]-5-methyl-4-oxo-4,5-dihydrothieno[3,2-c]pyridin-7-yl}-2-methoxyphenoxy)acetamide | non-polymer | 875.0 | 4 | Chemie (7P7) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 134 - 250 (UniProt: Q9H8M2)
| PDB | External Database | Details |
|---|---|---|
| Gly 130 | - | expression tag |
| Pro 131 | - | expression tag |
| His 132 | - | expression tag |
| Met 133 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 55231.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 3499.9 | |
| All* | Total formula weight | 58731.8 |
