5TUF

Crystal structure of tetracycline destructase Tet(50) in complex with anhydrotetracycline

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Tetracycline destructase Tet(50)	polymer	409	45982.2	2	UniProt (A0A059WYP6) Pfam (PF01494)	uncultured bacterium
2	C, D, E, F, H... (A, B)	SULFATE ION	non-polymer		96.1	7	Chemie (SO4)
3	G, K (A, B)	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	2	Chemie (FAD)
4	L (B)	5A,6-ANHYDROTETRACYCLINE	non-polymer		426.4	1	Chemie (TDC)
5	M, N (A, B)	water	water		18.0	337	Chemie (HOH)

Sequence modifications

A, B: 1 - 388 (UniProt: A0A059WYP6)

PDB	External Database	Details
Met -20	-	expression tag
Gly -19	-	expression tag
Ser -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Leu -7	-	expression tag
Val -6	-	expression tag
Pro -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	91964.4
Non-Polymers*	Number of molecules	10
	Total formula weight	2670.0
All*	Total formula weight	94634.4

*Water molecules are not included.