5TRU
Structure of the first-in-class checkpoint inhibitor Ipilimumab bound to human CTLA-4
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | L, l | Ipilimumab Fab light chain | polymer | 215 | 23477.0 | 2 | Homo sapiens | ||
2 | H, h | Ipilimumab Fab heavy chain | polymer | 225 | 24232.1 | 2 | Homo sapiens | ||
3 | c, C | Cytotoxic T-lymphocyte protein 4 | polymer | 118 | 12637.4 | 2 | UniProt (P16410) Pfam (PF07686) In PDB | Homo sapiens (Human) | Cytotoxic T-lymphocyte-associated antigen 4,CTLA-4 |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 120693.2 | |
All* | Total formula weight | 120693.2 |