5TRF
MDM2 in complex with SAR405838
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | E3 ubiquitin-protein ligase Mdm2 | polymer | 109 | 12506.4 | 5 | UniProt (Q00987) Pfam (PF02201) | Homo sapiens (Human) | Double minute 2 protein,Hdm2,Oncoprotein Mdm2,p53-binding protein Mdm2 |
| 2 | F, K, N, R, S (A, B, C, D, E) | (2'S,3R,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-N-(trans-4-hydroxycyclohexyl)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxamide | non-polymer | 562.5 | 5 | Chemie (7HC) PubChem (57329068) PubChem (57328982) PubChem (69888078) PubChem (90079158) PubChem (90181459) PubChem (52938482) PubChem (53476877) PubChem (124672825) PubChem (134693189) PubChem (155514420) PubChem (68347661) PubChem (68747447) PubChem (68752368) PubChem (69888109) PubChem (90181458) PubChem (125408806) PubChem (125408808) PubChem (126969377) PubChem (130215108) PubChem (134170302) PubChem (134450482) PubChem (137795971) PubChem (138660905) PubChem (154018573) PubChem (160588603) PubChem (166716393) | |||
| 3 | G, O, T (A, C, E) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | H, I, J, L, M... (A, B, C) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) PubChem (753) | |||
| 5 | U, V, W, X, Y (A, B, C, D, E) | water | water | 18.0 | 263 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 62531.8 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 3745.4 | |
| All* | Total formula weight | 66277.1 |
