5TRF
MDM2 in complex with SAR405838
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E | E3 ubiquitin-protein ligase Mdm2 | polymer | 109 | 12506.4 | 5 | UniProt (Q00987) Pfam (PF02201) In PDB | Homo sapiens (Human) | Double minute 2 protein,Hdm2,Oncoprotein Mdm2,p53-binding protein Mdm2 |
| 2 | A, B, C, D, E | (2'S,3R,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-N-(trans-4-hydroxycyclohexyl)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxamide | non-polymer | 562.5 | 5 | Chemie (7HC) | |||
| 3 | A, C, E | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | A, B, C | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 263 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 62531.8 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 3745.4 | |
| All* | Total formula weight | 66277.1 |
