5TIO
Crystal Structure of Human Glycine Receptor alpha-3 Bound to AM-3607
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | C, A, B, D, E | Glycine receptor subunit alpha-3 | polymer | 362 | 41857.4 | 5 | UniProt (O75311) Pfam (PF02931) Pfam (PF02932) In PDB | Homo sapiens (Human) | |
2 | C, A, B, D, E | (3S,3aS,9bS)-2-[(2H-1,3-benzodioxol-5-yl)sulfonyl]-3,5-dimethyl-1,2,3,3a,5,9b-hexahydro-4H-pyrrolo[3,4-c][1,6]naphthyridin-4-one | non-polymer | 401.4 | 5 | Chemie (7C6) | |||
3 | C, A, B, D, E | GLYCINE | non-polymer | 75.1 | 5 | Chemie (GLY) | |||
4 | C, A, B, D, E | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) | |||
5 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
C, A, B, D, E: 1 - 309 (UniProt: O75311)
C, A, B, D, E: 313 - 354 (UniProt: O75311)
C, A, B, D, E: 313 - 354 (UniProt: O75311)
PDB | External Database | Details |
---|---|---|
Ala 310 | - | linker |
Gly 311 | - | linker |
Thr 312 | - | linker |
Trp 355 | - | expression tag |
Ser 356 | - | expression tag |
His 357 | - | expression tag |
Pro 358 | - | expression tag |
Gln 359 | - | expression tag |
Phe 360 | - | expression tag |
Glu 361 | - | expression tag |
Lys 362 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 209287.0 | |
Non-Polymers* | Number of molecules | 16 |
Total formula weight | 2930.8 | |
All* | Total formula weight | 212217.8 |