5TEF

Crystal structure of Gemin5 WD40 repeats in complex with m7GpppG

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Gem-associated protein 5	polymer	758	84170.2	1	UniProt (Q8TEQ6) Pfam (PF00400) Pfam (PF21720) Pfam (PF12894)	Homo sapiens (Human)	Gemin5
2	B (A)	7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE	non-polymer		803.4	1	Chemie (GTG)
3	C, D, E (A)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
4	F, G, H, I, J... (A)	UNKNOWN ATOM OR ION	non-polymer			19	Chemie (UNX)
5	Y (A)	water	water		18.0	178	Chemie (HOH)

Sequence modifications

A: 1 - 739 (UniProt: Q8TEQ6)

PDB	External Database	Details
Met -18	-	initiating methionine
Gly -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
Leu -5	-	expression tag
Val -4	-	expression tag
Pro -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Gln 682	Arg 682	variant

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	84170.2
Non-Polymers*	Number of molecules	23
	Total formula weight	1079.7
All*	Total formula weight	85249.9

*Water molecules are not included.