5TCX

Crystal structure of human tetraspanin CD81

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	CD81 antigen	polymer	246	27203.6	1	UniProt (P60033) Pfam (PF00335)	Homo sapiens (Human)	26 kDa cell surface protein TAPA-1,Target of the antiproliferative antibody 1,Tetraspanin-28,Tspan-28
2	B (A)	CHOLESTEROL	non-polymer		386.7	1	Chemie (CLR)
3	C (A)	water	water		18.0	3	Chemie (HOH)

Sequence modifications

A: 2 - 236 (UniProt: P60033)

PDB	External Database	Details
Arg 1	-	expression tag
Ser 6	Cys 6	engineered mutation
Ser 9	Cys 9	engineered mutation
Ser 227	Cys 227	engineered mutation
Ser 228	Cys 228	engineered mutation
Val 237	-	expression tag
Pro 238	-	expression tag
His 239	-	expression tag
His 240	-	expression tag
His 241	-	expression tag
His 242	-	expression tag
His 243	-	expression tag
His 244	-	expression tag
His 245	-	expression tag
His 246	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	27203.6
Non-Polymers*	Number of molecules	1
	Total formula weight	386.7
All*	Total formula weight	27590.2

*Water molecules are not included.