5T8P
Crystal structure of murine NF-kappaB inducing kinase (NIK) bound to benzoxepin compound 2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Mitogen-activated protein kinase kinase kinase 14 | polymer | 349 | 38543.4 | 2 | UniProt (Q9WUL6) Pfam (PF00069) | Mus musculus (Mouse) | NF-kappa-beta-inducing kinase,Serine/threonine-protein kinase NIK |
| 2 | C, H (A, B) | 6,7-dihydrothieno[4,5]oxepino[1,2-~{c}]pyridine-2-carboxamide | non-polymer | 246.3 | 2 | Chemie (774) | |||
| 3 | D, E, F, G (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | I, J (A, B) | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence modifications
A, B: 329 - 675 (UniProt: Q9WUL6)
| PDB | External Database | Details |
|---|---|---|
| Gly 327 | - | expression tag |
| Ser 328 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 77086.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 876.8 | |
| All* | Total formula weight | 77963.7 |
