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5T2O

Engineered variant of I-OnuI meganuclease targeting the Anopheles AGAP011377 gene; harbors 53 point mutations relative to wild-type I-OnuI

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
I-OnuI_e-ag011377polymer30234891.41synthetic construct
2B
(B)
DNA (26-MER)polymer268044.21synthetic construct
3C
(C)
DNA (26-MER)polymer267933.11synthetic construct
4D, E
(A)
CALCIUM IONnon-polymer40.12Chemie (CA)
5F, G, H
(A, B, C)
waterwater18.013Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight50868.7
Non-Polymers*Number of molecules2
Total formula weight80.2
All*Total formula weight50948.9
*Water molecules are not included.

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PDB entries from 2025-06-25

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