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5T2O

Engineered variant of I-OnuI meganuclease targeting the Anopheles AGAP011377 gene; harbors 53 point mutations relative to wild-type I-OnuI

Functional Information from GO Data
ChainGOidnamespacecontents
A0004519molecular_functionendonuclease activity
Functional Information from PDB Data
site_idAC1
Number of Residues5
Detailsbinding site for residue CA A 401
ChainResidue
AALA21
AGLU178
BDC14
CDT16
CHOH103

site_idAC2
Number of Residues4
Detailsbinding site for residue CA A 402
ChainResidue
AGLU22
AGLY177
BDT15
CDA15

227344

PDB entries from 2024-11-13

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