5T0U

CTCF ZnF2-7 and DNA complex structure

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	Transcriptional repressor CTCF	polymer	177	20720.0	2	UniProt (P49711) Pfam (PF00096) In PDB	Homo sapiens (Human)	11-zinc finger protein,CCCTC-binding factor,CTCFL paralog
2	B, E	DNA (5'-D(*CP*CP*TP*CP*AP*CP*TP*AP*GP*CP*GP*CP*CP*CP*CP*CP*TP*GP*CP*TP*GP*GP*C)-3')	polymer	23	6914.4	2		synthetic construct
3	C, F	DNA (5'-D(*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*GP*GP*CP*GP*CP*TP*AP*GP*TP*GP*AP*GP*G)-3')	polymer	23	7212.6	2		synthetic construct
4	A, D	ZINC ION	non-polymer		65.4	12	Chemie (ZN)
5		water	water		18.0	12	Chemie (HOH)

Sequence modifications

A, D: 294 - 465 (UniProt: P49711)

PDB	External Database	Details
Pro 289	-	expression tag
Leu 290	-	expression tag
Gly 291	-	expression tag
Ser 292	-	expression tag
Thr 293	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	69694.2
Non-Polymers*	Number of molecules	12
	Total formula weight	784.9
All*	Total formula weight	70479.1

*Water molecules are not included.