5T0U

CTCF ZnF2-7 and DNA complex structure

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 501

Chain	Residue
A	CYS296
A	CYS299
A	HIS312
A	HIS316

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 502

Chain	Residue
A	CYS324
A	CYS327
A	HIS340
A	HIS345

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN A 503

Chain	Residue
A	CYS356
A	HIS369
A	HIS373
A	CYS353

---

site_id	AC4
Number of Residues	4
Details	binding site for residue ZN A 504

Chain	Residue
A	CYS381
A	CYS384
A	HIS397
A	HIS401

---

site_id	AC5
Number of Residues	4
Details	binding site for residue ZN A 505

Chain	Residue
A	CYS409
A	CYS412
A	HIS425
A	HIS430

---

site_id	AC6
Number of Residues	4
Details	binding site for residue ZN A 506

Chain	Residue
A	CYS439
A	CYS442
A	HIS455
A	HIS460

---

site_id	AC7
Number of Residues	4
Details	binding site for residue ZN D 501

Chain	Residue
D	CYS296
D	CYS299
D	HIS312
D	HIS316

---

site_id	AC8
Number of Residues	5
Details	binding site for residue ZN D 502

Chain	Residue
D	CYS324
D	ASP326
D	CYS327
D	HIS340
D	HIS345

---

site_id	AC9
Number of Residues	4
Details	binding site for residue ZN D 503

Chain	Residue
D	CYS353
D	CYS356
D	HIS369
D	HIS373

---

site_id	AD1
Number of Residues	4
Details	binding site for residue ZN D 504

Chain	Residue
D	CYS381
D	CYS384
D	HIS397
D	HIS401

---

site_id	AD2
Number of Residues	4
Details	binding site for residue ZN D 505

Chain	Residue
D	CYS409
D	CYS412
D	HIS425
D	HIS430

---

site_id	AD3
Number of Residues	4
Details	binding site for residue ZN D 506

Chain	Residue
D	CYS439
D	CYS442
D	HIS455
D	HIS460

---

Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	21
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Chl..CgraFrtvtllrnHlnt..H

Chain	Residue	Details
A	CYS296-HIS316
A	CYS324-HIS345
A	CYS409-HIS430
A	CYS439-HIS460

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	44
Details	ZN_FING: C2H2-type 2 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
A	HIS294-HIS316
D	HIS294-HIS316

---

site_id	SWS_FT_FI2
Number of Residues	46
Details	ZN_FING: C2H2-type 3 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
A	HIS322-HIS345
D	HIS322-HIS345

---

site_id	SWS_FT_FI3
Number of Residues	44
Details	ZN_FING: C2H2-type 4 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
A	PHE351-HIS373
D	PHE351-HIS373

---

site_id	SWS_FT_FI4
Number of Residues	44
Details	ZN_FING: C2H2-type 5 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
A	PHE379-HIS401
D	PHE379-HIS401

---

site_id	SWS_FT_FI5
Number of Residues	46
Details	ZN_FING: C2H2-type 6 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
A	TYR407-HIS430
D	TYR407-HIS430

---

site_id	SWS_FT_FI6
Number of Residues	46
Details	ZN_FING: C2H2-type 7 => ECO:0000255|PROSITE-ProRule:PRU00042

Chain	Residue	Details
A	PHE437-HIS460
D	PHE437-HIS460

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231

Chain	Residue	Details
A	THR317
D	THR317

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648

Chain	Residue	Details
A	THR374
D	THR374

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648

Chain	Residue	Details
A	SER402
D	SER402

---