5SYM
Cocrystal structure of the human acyl protein thioesterase 1 with an isoform-selective inhibitor, ML348
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Acyl-protein thioesterase 1 | polymer | 230 | 24692.5 | 2 | UniProt (O75608) Pfam (PF02230) In PDB | Homo sapiens (Human) | hAPT1,Lysophospholipase 1,Lysophospholipase I,LysoPLA I |
| 2 | A, B | N-[2-chloro-5-(trifluoromethyl)phenyl]-2-[4-(furan-2-carbonyl)piperazin-1-yl]acetamide | non-polymer | 415.8 | 2 | Chemie (71Q) | |||
| 3 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 4 | A, B | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 5 | water | water | 18.0 | 363 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 49385.1 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1407.9 | |
| All* | Total formula weight | 50793.0 |
