5Q0C

Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-[5-(4-methoxyphenyl)thiophen-2-yl]sulfonylurea and with fructose-2,6-diphosphate

Entity

Chain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
A, B, C, D, E...Fructose-1,6-bisphosphatase isozyme 2polymer33936798.18
UniProt (O00757)
Pfam (PF00316)
Homo sapiens (Human)FBPase 2,D-fructose-1,6-bisphosphate 1-phosphohydrolase 2,Muscle FBPase
N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-5-(4-methoxyphenyl)thiophene-2-sulfonamidenon-polymer474.48
FRUCTOSE-2,6-DIPHOSPHATEnon-polymer340.18
waterwater18.0545

Sequence viewer

Contents of the asymmetric unit

PolymersNumber of chains8
Total molecular weight294384.8
Non-Polymers*Number of molecules16
Total molecular weight6515.9
All*Total molecular weight300900.7
*Water molecules are not included.
PDBj@FacebookPDBj@TwitterwwPDBwwPDB Foundation

Copyright © 2013-2019 Protein Data Bank Japan