5Q0C

Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-[5-(4-methoxyphenyl)thiophen-2-yl]sulfonylurea and with fructose-2,6-diphosphate

Refinement Statistics

Experimental method:X-RAY DIFFRACTION (2.4 Å)

Cell axes222.475240.518138.979
Cell angles90.0090.0090.00
SpacegroupC 2 2 21
Resolution limits29.79 - 2.40
the highest resolution shell value2.427 - 2.400
R-factor0.1703
R-work0.16820
the highest resolution shell value0.253
R-free0.21030
the highest resolution shell value0.301
RMSD bond length0.008
RMSD bond angle0.960

Data Collection Statistics

Resolution limits29.79 - 2.40
the highest resolution shell value -
Number of reflections141184
Completeness97.5

Crystallization Conditions

crystal IDmethodpHpH rangetemperatureunit
1VAPOR DIFFUSION, SITTING DROP

Crystallization Reagents

IDcrystal IDsolution IDreagent nameconcentrationdetails
Crystallization Reagents in Literatures*
IDcrystal IDsolutionreagent nameconcentration (unit)details
Annotated Information is extracted from Literature Info*
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