5OYH

crystal structure of the catalytic core of a rhodopsin-guanylyl cyclase with converted specificity in complex with ATPalphaS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Nucleotide cyclase	polymer	193	21553.6	16	UniProt (A0A1Y2HEJ3) Pfam (PF00211) In PDB	Catenaria anguillulae PL171
2	D, L, M, E, N...	ADENOSINE-5'-SP-ALPHA-THIO-TRIPHOSPHATE	non-polymer		523.2	16	Chemie (T99)
3	L, D, M, E, N...	CALCIUM ION	non-polymer		40.1	16	Chemie (CA)
4	D, E, F, O, G...	GLYCEROL	non-polymer		92.1	15	Chemie (GOL)
5		water	water		18.0	1715	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P: 443 - 626 (UniProt: A0A1Y2HEJ3)

PDB	External Database	Details
Met 442	-	initiating methionine
Lys 497	Glu 132	engineered mutation
Asp 566	Cys 201	engineered mutation
Leu 627	-	expression tag
Glu 628	-	expression tag
His 629	-	expression tag
His 630	-	expression tag
His 631	-	expression tag
His 632	-	expression tag
His 633	-	expression tag
His 634	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	344857.4
Non-Polymers*	Number of molecules	47
	Total formula weight	10394.6
All*	Total formula weight	355252.0

*Water molecules are not included.