5OYH
crystal structure of the catalytic core of a rhodopsin-guanylyl cyclase with converted specificity in complex with ATPalphaS
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0009190 | biological_process | cyclic nucleotide biosynthetic process |
| A | 0035556 | biological_process | intracellular signal transduction |
| B | 0009190 | biological_process | cyclic nucleotide biosynthetic process |
| B | 0035556 | biological_process | intracellular signal transduction |
| C | 0009190 | biological_process | cyclic nucleotide biosynthetic process |
| C | 0035556 | biological_process | intracellular signal transduction |
| D | 0009190 | biological_process | cyclic nucleotide biosynthetic process |
| D | 0035556 | biological_process | intracellular signal transduction |
| E | 0009190 | biological_process | cyclic nucleotide biosynthetic process |
| E | 0035556 | biological_process | intracellular signal transduction |
| F | 0009190 | biological_process | cyclic nucleotide biosynthetic process |
| F | 0035556 | biological_process | intracellular signal transduction |
| G | 0009190 | biological_process | cyclic nucleotide biosynthetic process |
| G | 0035556 | biological_process | intracellular signal transduction |
| H | 0009190 | biological_process | cyclic nucleotide biosynthetic process |
| H | 0035556 | biological_process | intracellular signal transduction |
| I | 0009190 | biological_process | cyclic nucleotide biosynthetic process |
| I | 0035556 | biological_process | intracellular signal transduction |
| J | 0009190 | biological_process | cyclic nucleotide biosynthetic process |
| J | 0035556 | biological_process | intracellular signal transduction |
| K | 0009190 | biological_process | cyclic nucleotide biosynthetic process |
| K | 0035556 | biological_process | intracellular signal transduction |
| L | 0009190 | biological_process | cyclic nucleotide biosynthetic process |
| L | 0035556 | biological_process | intracellular signal transduction |
| M | 0009190 | biological_process | cyclic nucleotide biosynthetic process |
| M | 0035556 | biological_process | intracellular signal transduction |
| N | 0009190 | biological_process | cyclic nucleotide biosynthetic process |
| N | 0035556 | biological_process | intracellular signal transduction |
| O | 0009190 | biological_process | cyclic nucleotide biosynthetic process |
| O | 0035556 | biological_process | intracellular signal transduction |
| P | 0009190 | biological_process | cyclic nucleotide biosynthetic process |
| P | 0035556 | biological_process | intracellular signal transduction |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | binding site for residue T99 A 701 |
| Chain | Residue |
| A | ASP457 |
| A | CA702 |
| A | HOH801 |
| A | HOH803 |
| A | HOH809 |
| A | HOH837 |
| B | LYS497 |
| B | LEU504 |
| B | ASP566 |
| B | LEU567 |
| B | VAL572 |
| A | ILE458 |
| B | ASN573 |
| B | SER576 |
| B | ARG577 |
| B | HOH860 |
| B | HOH875 |
| A | THR459 |
| A | ASN460 |
| A | PHE461 |
| A | THR462 |
| A | ILE499 |
| A | ASP501 |
| A | ARG545 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 702 |
| Chain | Residue |
| A | ASP457 |
| A | ILE458 |
| A | ASP501 |
| A | T99701 |
| A | HOH803 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 703 |
| Chain | Residue |
| A | THR470 |
| A | HOH804 |
| A | HOH847 |
| A | HOH857 |
| A | HOH863 |
| B | GLU447 |
| B | VAL553 |
| B | THR554 |
| D | GLN595 |
| D | MET596 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 704 |
| Chain | Residue |
| A | GLU447 |
| A | VAL553 |
| A | THR554 |
| A | HOH842 |
| A | HOH870 |
| B | THR470 |
| B | HOH874 |
| E | GLN595 |
| E | MET596 |
| E | HOH811 |
| site_id | AC5 |
| Number of Residues | 21 |
| Details | binding site for residue T99 B 701 |
| Chain | Residue |
| A | LYS497 |
| A | ASP566 |
| A | LEU567 |
| A | VAL572 |
| A | ASN573 |
| A | SER576 |
| A | ARG577 |
| A | HOH849 |
| B | ASP457 |
| B | ILE458 |
| B | THR459 |
| B | ASN460 |
| B | PHE461 |
| B | THR462 |
| B | ILE499 |
| B | ASP501 |
| B | ARG545 |
| B | CA702 |
| B | HOH802 |
| B | HOH804 |
| B | HOH843 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 702 |
| Chain | Residue |
| B | ASP457 |
| B | ILE458 |
| B | ASP501 |
| B | T99701 |
| B | HOH804 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for residue GOL C 701 |
| Chain | Residue |
| C | GLN595 |
| C | MET596 |
| C | HOH860 |
| C | HOH866 |
| C | HOH878 |
| G | GLU447 |
| G | VAL553 |
| G | THR554 |
| H | THR470 |
| site_id | AC8 |
| Number of Residues | 21 |
| Details | binding site for residue T99 C 702 |
| Chain | Residue |
| D | LEU567 |
| D | VAL572 |
| D | ASN573 |
| D | SER576 |
| D | ARG577 |
| D | HOH878 |
| C | ASP457 |
| C | ILE458 |
| C | ASN460 |
| C | PHE461 |
| C | THR462 |
| C | ILE499 |
| C | GLY500 |
| C | ASP501 |
| C | ARG545 |
| C | CA703 |
| C | HOH823 |
| C | HOH834 |
| C | HOH883 |
| D | LYS497 |
| D | ASP566 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue CA C 703 |
| Chain | Residue |
| C | ASP457 |
| C | ILE458 |
| C | ASP501 |
| C | T99702 |
| C | HOH883 |
| site_id | AD1 |
| Number of Residues | 8 |
| Details | binding site for residue GOL C 704 |
| Chain | Residue |
| B | GLN595 |
| B | MET596 |
| C | THR470 |
| C | HOH833 |
| C | HOH869 |
| C | HOH872 |
| C | HOH885 |
| D | THR554 |
| site_id | AD2 |
| Number of Residues | 22 |
| Details | binding site for residue T99 D 701 |
| Chain | Residue |
| C | LYS497 |
| C | ASP566 |
| C | LEU567 |
| C | VAL572 |
| C | ASN573 |
| C | SER576 |
| C | HOH854 |
| C | HOH859 |
| D | ASP457 |
| D | ILE458 |
| D | THR459 |
| D | ASN460 |
| D | PHE461 |
| D | THR462 |
| D | ILE499 |
| D | ASP501 |
| D | ARG545 |
| D | CA703 |
| D | HOH801 |
| D | HOH806 |
| D | HOH867 |
| D | HOH875 |
| site_id | AD3 |
| Number of Residues | 10 |
| Details | binding site for residue GOL D 702 |
| Chain | Residue |
| C | GLU447 |
| C | PRO552 |
| C | VAL553 |
| C | THR554 |
| D | THR470 |
| D | HOH819 |
| D | HOH889 |
| G | GLN595 |
| G | MET596 |
| G | HOH878 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue CA D 703 |
| Chain | Residue |
| D | ASP457 |
| D | ILE458 |
| D | ASP501 |
| D | T99701 |
| D | HOH806 |
| site_id | AD5 |
| Number of Residues | 23 |
| Details | binding site for residue T99 E 701 |
| Chain | Residue |
| E | ASP457 |
| E | ILE458 |
| E | ASN460 |
| E | PHE461 |
| E | THR462 |
| E | ILE499 |
| E | ASP501 |
| E | ARG545 |
| E | CA702 |
| E | HOH801 |
| E | HOH844 |
| E | HOH848 |
| E | HOH851 |
| E | HOH855 |
| F | LYS497 |
| F | LEU504 |
| F | ASP566 |
| F | LEU567 |
| F | VAL572 |
| F | ASN573 |
| F | SER576 |
| F | ARG577 |
| F | HOH878 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue CA E 702 |
| Chain | Residue |
| E | ASP457 |
| E | ILE458 |
| E | ASP501 |
| E | T99701 |
| E | HOH851 |
| site_id | AD7 |
| Number of Residues | 7 |
| Details | binding site for residue GOL E 703 |
| Chain | Residue |
| A | GLN595 |
| A | MET596 |
| A | HOH851 |
| E | GLU447 |
| E | THR554 |
| E | HOH830 |
| F | THR470 |
| site_id | AD8 |
| Number of Residues | 8 |
| Details | binding site for residue GOL F 701 |
| Chain | Residue |
| E | THR470 |
| F | GLU447 |
| F | THR554 |
| F | HOH853 |
| F | HOH868 |
| M | GLN595 |
| M | MET596 |
| M | HOH817 |
| site_id | AD9 |
| Number of Residues | 23 |
| Details | binding site for residue T99 F 702 |
| Chain | Residue |
| E | LYS497 |
| E | ASP566 |
| E | LEU567 |
| E | VAL572 |
| E | ASN573 |
| E | SER576 |
| E | ARG577 |
| E | HOH836 |
| F | ASP457 |
| F | ILE458 |
| F | THR459 |
| F | ASN460 |
| F | PHE461 |
| F | THR462 |
| F | ILE499 |
| F | GLY500 |
| F | ASP501 |
| F | ARG545 |
| F | CA704 |
| F | HOH801 |
| F | HOH806 |
| F | HOH834 |
| F | HOH863 |
| site_id | AE1 |
| Number of Residues | 10 |
| Details | binding site for residue GOL F 703 |
| Chain | Residue |
| F | GLN595 |
| F | MET596 |
| F | HOH813 |
| F | HOH843 |
| F | HOH876 |
| M | GLU447 |
| M | VAL553 |
| M | THR554 |
| M | HOH844 |
| N | THR470 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue CA F 704 |
| Chain | Residue |
| F | ASP457 |
| F | ILE458 |
| F | ASP501 |
| F | T99702 |
| F | HOH806 |
| site_id | AE3 |
| Number of Residues | 22 |
| Details | binding site for residue T99 G 701 |
| Chain | Residue |
| G | ASP457 |
| G | ILE458 |
| G | ASN460 |
| G | PHE461 |
| G | THR462 |
| G | ILE499 |
| G | GLY500 |
| G | ASP501 |
| G | ARG545 |
| G | CA702 |
| G | HOH804 |
| G | HOH815 |
| G | HOH817 |
| G | HOH821 |
| H | LYS497 |
| H | ASP566 |
| H | LEU567 |
| H | VAL572 |
| H | ASN573 |
| H | SER576 |
| H | ARG577 |
| H | HOH884 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue CA G 702 |
| Chain | Residue |
| G | ASP457 |
| G | ILE458 |
| G | ASP501 |
| G | T99701 |
| G | HOH817 |
| site_id | AE5 |
| Number of Residues | 9 |
| Details | binding site for residue GOL G 703 |
| Chain | Residue |
| G | THR470 |
| G | HOH844 |
| G | HOH852 |
| G | HOH868 |
| G | HOH872 |
| H | GLU447 |
| H | THR554 |
| L | GLN595 |
| L | MET596 |
| site_id | AE6 |
| Number of Residues | 24 |
| Details | binding site for residue T99 H 701 |
| Chain | Residue |
| G | LYS497 |
| G | LEU504 |
| G | ASP566 |
| G | LEU567 |
| G | VAL572 |
| G | ASN573 |
| G | SER576 |
| G | ARG577 |
| G | HOH862 |
| H | ASP457 |
| H | ILE458 |
| H | THR459 |
| H | ASN460 |
| H | PHE461 |
| H | THR462 |
| H | ILE499 |
| H | ASP501 |
| H | ARG545 |
| H | CA702 |
| H | HOH801 |
| H | HOH804 |
| H | HOH807 |
| H | HOH809 |
| H | HOH820 |
| site_id | AE7 |
| Number of Residues | 5 |
| Details | binding site for residue CA H 702 |
| Chain | Residue |
| H | ASP457 |
| H | ILE458 |
| H | ASP501 |
| H | T99701 |
| H | HOH804 |
| site_id | AE8 |
| Number of Residues | 9 |
| Details | binding site for residue GOL I 701 |
| Chain | Residue |
| I | GLN595 |
| I | MET596 |
| I | HOH835 |
| I | HOH839 |
| I | HOH845 |
| M | THR470 |
| N | GLU447 |
| N | VAL553 |
| N | THR554 |
| site_id | AE9 |
| Number of Residues | 24 |
| Details | binding site for residue T99 I 702 |
| Chain | Residue |
| I | ASP457 |
| I | ILE458 |
| I | ASN460 |
| I | PHE461 |
| I | THR462 |
| I | ILE499 |
| I | GLY500 |
| I | ASP501 |
| I | ARG545 |
| I | CA703 |
| I | HOH805 |
| I | HOH812 |
| I | HOH825 |
| I | HOH844 |
| J | LYS497 |
| J | LEU504 |
| J | ASP566 |
| J | LEU567 |
| J | VAL572 |
| J | ASN573 |
| J | SER576 |
| J | ARG577 |
| J | HOH857 |
| J | HOH873 |
| site_id | AF1 |
| Number of Residues | 4 |
| Details | binding site for residue CA I 703 |
| Chain | Residue |
| I | ASP457 |
| I | ILE458 |
| I | ASP501 |
| I | T99702 |
| site_id | AF2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL J 701 |
| Chain | Residue |
| I | GLU447 |
| I | THR554 |
| J | THR470 |
| J | HOH835 |
| J | HOH869 |
| N | GLN595 |
| N | MET596 |
| N | HOH818 |
| site_id | AF3 |
| Number of Residues | 10 |
| Details | binding site for residue GOL J 702 |
| Chain | Residue |
| I | THR470 |
| J | GLU447 |
| J | VAL553 |
| J | THR554 |
| J | HOH845 |
| J | HOH864 |
| J | HOH872 |
| O | GLN595 |
| O | MET596 |
| O | HOH833 |
| site_id | AF4 |
| Number of Residues | 20 |
| Details | binding site for residue T99 J 703 |
| Chain | Residue |
| I | LYS497 |
| I | ASP566 |
| I | LEU567 |
| I | VAL572 |
| I | ASN573 |
| I | SER576 |
| I | ARG577 |
| I | HOH859 |
| J | ASP457 |
| J | ILE458 |
| J | ASN460 |
| J | PHE461 |
| J | THR462 |
| J | ILE499 |
| J | GLY500 |
| J | ASP501 |
| J | ARG545 |
| J | CA704 |
| J | HOH801 |
| J | HOH833 |
| site_id | AF5 |
| Number of Residues | 4 |
| Details | binding site for residue CA J 704 |
| Chain | Residue |
| J | ASP457 |
| J | ILE458 |
| J | ASP501 |
| J | T99703 |
| site_id | AF6 |
| Number of Residues | 22 |
| Details | binding site for residue T99 K 701 |
| Chain | Residue |
| K | ASP457 |
| K | ILE458 |
| K | ASN460 |
| K | PHE461 |
| K | THR462 |
| K | ILE499 |
| K | ASP501 |
| K | ARG545 |
| K | CA702 |
| K | HOH801 |
| K | HOH803 |
| K | HOH819 |
| L | LYS497 |
| L | LEU504 |
| L | ASP566 |
| L | LEU567 |
| L | VAL572 |
| L | ASN573 |
| L | SER576 |
| L | ARG577 |
| L | HOH840 |
| L | HOH872 |
| site_id | AF7 |
| Number of Residues | 5 |
| Details | binding site for residue CA K 702 |
| Chain | Residue |
| K | ASP457 |
| K | ILE458 |
| K | ASP501 |
| K | T99701 |
| K | HOH819 |
| site_id | AF8 |
| Number of Residues | 7 |
| Details | binding site for residue GOL K 703 |
| Chain | Residue |
| K | VAL553 |
| K | THR554 |
| K | HOH818 |
| K | HOH843 |
| L | THR470 |
| P | GLN595 |
| P | MET596 |
| site_id | AF9 |
| Number of Residues | 10 |
| Details | binding site for residue GOL L 701 |
| Chain | Residue |
| H | GLN595 |
| H | MET596 |
| K | THR470 |
| L | GLU447 |
| L | VAL553 |
| L | THR554 |
| L | HOH845 |
| L | HOH865 |
| L | HOH871 |
| L | HOH880 |
| site_id | AG1 |
| Number of Residues | 22 |
| Details | binding site for residue T99 L 702 |
| Chain | Residue |
| K | LYS497 |
| K | LEU504 |
| K | ASP566 |
| K | LEU567 |
| K | VAL572 |
| K | ASN573 |
| K | SER576 |
| K | ARG577 |
| K | HOH816 |
| L | ASP457 |
| L | ILE458 |
| L | ASN460 |
| L | PHE461 |
| L | THR462 |
| L | ILE499 |
| L | ASP501 |
| L | ARG545 |
| L | CA703 |
| L | HOH801 |
| L | HOH802 |
| L | HOH806 |
| L | HOH856 |
| site_id | AG2 |
| Number of Residues | 5 |
| Details | binding site for residue CA L 703 |
| Chain | Residue |
| L | ASP457 |
| L | ILE458 |
| L | ASP501 |
| L | T99702 |
| L | HOH802 |
| site_id | AG3 |
| Number of Residues | 21 |
| Details | binding site for residue T99 M 701 |
| Chain | Residue |
| M | ASP457 |
| M | ILE458 |
| M | ASN460 |
| M | PHE461 |
| M | THR462 |
| M | ILE499 |
| M | ASP501 |
| M | ARG545 |
| M | CA702 |
| M | HOH802 |
| M | HOH820 |
| M | HOH837 |
| M | HOH872 |
| N | LYS497 |
| N | LEU504 |
| N | ASP566 |
| N | LEU567 |
| N | VAL572 |
| N | ASN573 |
| N | SER576 |
| N | ARG577 |
| site_id | AG4 |
| Number of Residues | 5 |
| Details | binding site for residue CA M 702 |
| Chain | Residue |
| M | ASP457 |
| M | ILE458 |
| M | ASP501 |
| M | T99701 |
| M | HOH820 |
| site_id | AG5 |
| Number of Residues | 21 |
| Details | binding site for residue T99 N 701 |
| Chain | Residue |
| M | LYS497 |
| M | LEU504 |
| M | ASP566 |
| M | LEU567 |
| M | VAL572 |
| M | ASN573 |
| M | SER576 |
| M | ARG577 |
| M | HOH866 |
| N | ASP457 |
| N | ILE458 |
| N | ASN460 |
| N | PHE461 |
| N | THR462 |
| N | ILE499 |
| N | GLY500 |
| N | ASP501 |
| N | ARG545 |
| N | CA702 |
| N | HOH802 |
| N | HOH823 |
| site_id | AG6 |
| Number of Residues | 5 |
| Details | binding site for residue CA N 702 |
| Chain | Residue |
| N | ASP457 |
| N | ILE458 |
| N | ASP501 |
| N | T99701 |
| N | HOH823 |
| site_id | AG7 |
| Number of Residues | 19 |
| Details | binding site for residue T99 O 701 |
| Chain | Residue |
| O | ASP457 |
| O | ILE458 |
| O | THR459 |
| O | ASN460 |
| O | PHE461 |
| O | THR462 |
| O | ILE499 |
| O | ASP501 |
| O | ARG545 |
| O | CA702 |
| O | HOH835 |
| P | LYS497 |
| P | ASP566 |
| P | LEU567 |
| P | VAL572 |
| P | ASN573 |
| P | SER576 |
| P | HOH825 |
| P | HOH835 |
| site_id | AG8 |
| Number of Residues | 4 |
| Details | binding site for residue CA O 702 |
| Chain | Residue |
| O | ASP457 |
| O | ILE458 |
| O | ASP501 |
| O | T99701 |
| site_id | AG9 |
| Number of Residues | 10 |
| Details | binding site for residue GOL O 703 |
| Chain | Residue |
| J | GLN595 |
| J | MET596 |
| O | GLU447 |
| O | VAL553 |
| O | THR554 |
| O | HOH811 |
| O | HOH824 |
| O | HOH828 |
| O | HOH844 |
| P | THR470 |
| site_id | AH1 |
| Number of Residues | 21 |
| Details | binding site for residue T99 P 701 |
| Chain | Residue |
| O | LYS497 |
| O | ASP566 |
| O | LEU567 |
| O | VAL572 |
| O | ASN573 |
| O | SER576 |
| O | ARG577 |
| O | HOH848 |
| O | HOH853 |
| P | ASP457 |
| P | ILE458 |
| P | ASN460 |
| P | PHE461 |
| P | THR462 |
| P | ILE499 |
| P | ASP501 |
| P | ARG545 |
| P | CA702 |
| P | HOH801 |
| P | HOH804 |
| P | HOH814 |
| site_id | AH2 |
| Number of Residues | 5 |
| Details | binding site for residue CA P 702 |
| Chain | Residue |
| P | ASP457 |
| P | ILE458 |
| P | ASP501 |
| P | T99701 |
| P | HOH801 |
