5OWA
Crystal structure of the human BRPF1 bromodomain in complex with BZ054
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Peregrin | polymer | 116 | 13703.7 | 4 | UniProt (P55201) Pfam (PF00439) In PDB | Homo sapiens (Human) | Bromodomain and PHD finger-containing protein 1,Protein Br140 |
| 2 | A, B, C | ~{N}-[4-[[(3~{S},5~{R})-3,5-dimethylpiperidin-1-yl]methyl]-1,3-thiazol-2-yl]-2,4-dimethyl-1,3-oxazole-5-carboxamide | non-polymer | 348.5 | 3 | Chemie (B0H) | |||
| 3 | water | water | 18.0 | 341 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 626 - 740 (UniProt: P55201)
| PDB | External Database | Details |
|---|---|---|
| Ser 625 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 54814.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1045.4 | |
| All* | Total formula weight | 55860.2 |
