5OWA
Crystal structure of the human BRPF1 bromodomain in complex with BZ054
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue B0H A 801 |
| Chain | Residue |
| A | ILE652 |
| A | HOH937 |
| C | GLU683 |
| C | TYR685 |
| A | PHE653 |
| A | VAL657 |
| A | PRO658 |
| A | VAL662 |
| A | ASN708 |
| A | PHE714 |
| A | HOH926 |
| A | HOH927 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue B0H B 801 |
| Chain | Residue |
| B | PHE653 |
| B | VAL657 |
| B | VAL662 |
| B | TYR707 |
| B | ASN708 |
| B | PHE714 |
| B | HOH944 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue B0H C 801 |
| Chain | Residue |
| C | PHE653 |
| C | VAL657 |
| C | PRO658 |
| C | GLU661 |
| C | VAL662 |
| C | CYS704 |
| C | TYR707 |
| C | ASN708 |
| C | PHE714 |
| C | HOH926 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 58 |
| Details | BROMODOMAIN_1 Bromodomain signature. GniFsepvPlsevp..DYLdhIkkpMdfftMkqnleayr..Ylnfddfeedfnl.IvsNClkY |
| Chain | Residue | Details |
| A | GLY650-TYR707 |
