5OSC
GLIC-GABAAR alpha1 chimera crystallized in complex with pregnenolone sulfate at pH 4.5
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E | Proton-gated ion channel,Gamma-aminobutyric acid receptor subunit alpha-2,Gamma-aminobutyric acid receptor subunit alpha-1 | polymer | 336 | 38644.2 | 5 | UniProt (Q7NDN8) UniProt (P26048) UniProt (P62812) Pfam (PF02931) Pfam (PF02932) In PDB | Gloeobacter violaceus (strain PCC 7421) | GLIC,Ligand-gated ion channel,LGIC,GABA(A) receptor subunit alpha-2,GABA(A) receptor subunit alpha-1 |
2 | A, B, C, D, E | ACETATE ION | non-polymer | 59.0 | 8 | Chemie (ACT) | |||
3 | A, B, C, D, E | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
4 | E, A, B, C, D | Pregnenolone sulfate | non-polymer | 396.5 | 5 | Chemie (A8W) | |||
5 | E, A, B, D | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 5 | Chemie (Y01) |
Sequence modifications
A, B, C, D, E: 1 - 193 (UniProt: Q7NDN8)
A, B, C, D, E: 223 - 311 (UniProt: P26048)
A, B, C, D, E: 390 - 428 (UniProt: P62812)
A, B, C, D, E: 223 - 311 (UniProt: P26048)
PDB | External Database | Details |
---|---|---|
Val 258 | Gly 286 | conflict |
Ser 312 | - | linker |
Gln 313 | - | linker |
Pro 314 | - | linker |
Ala 315 | - | linker |
Arg 316 | - | linker |
Ala 317 | - | linker |
Ala 318 | - | linker |
PDB | External Database | Details |
---|---|---|
His 429 | - | expression tag |
His 430 | - | expression tag |
His 431 | - | expression tag |
His 432 | - | expression tag |
His 433 | - | expression tag |
His 434 | - | expression tag |
His 435 | - | expression tag |
His 436 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 193220.9 | |
Non-Polymers* | Number of molecules | 23 |
Total formula weight | 5066.0 | |
All* | Total formula weight | 198286.9 |